A strong solar flare measuring M9.6 erupted from Active Region 2975 at 18:35 UTC on March 31, 2022. The event started at 18:17 UTC and ended at 18:45. A Type II Radio Emission with an estimated velocity of 1 627 km/s was registered at 18:34 UTC. Type II emissions...... Read more

A very strong and shallow earthquake registered by the USGS as M7.0 hit southeast of the Loyalty Islands, New Caledonia at 05:44 UTC on March 31, 2022. The agency is reporting a depth of 10 km (6.2 miles). EMSC is reporting the same magnitude and depth. The quake...... Read more

A major solar flare measuring X1.3 erupted from Active Region 2975 at 17:37 UTC on March 30, 2022. The event started at 17:21 UTC and ended at 17:46. The region is located in an area that favors Earth-directed coronal mass ejections (CMEs). A Type II Radio Emission...... Read more

Active Region 2975 produced multiple C- and M-class solar flares since M4.0 at 11:29 UTC on March 28, 2022, as well as 2 coronal mass ejections (CMEs) - both toward Earth. As a result, a G3 - Strong geomagnetic storm watch is in effect for March 31. Solar activity...... Read more

Heavy rainfall affecting southern Ecuador, particularly the province of Azuay, over the past 48 hours caused numerous landslides resulting in casualties and damage. On March 28, the Servicio Nacional de Gestin de Riesgos reported 4 fatalities, 4 injured...... Read more

A new eruption has started at the underwater Funka Asane vent near Kita-Ioto volcano, Japan on Sunday, March 27, 2022. The last confirmed eruption at this volcano lasted from 1930 to 1945 (VEI 2). The eruption started at around 09:00 UTC on March 27, with ash rising...... Read more

A moderately-strong solar flare measuring M4.0 erupted from geoeffective Active Region 2975 at 11:29 UTC on March 28, 2022. The event started at 10:58 UTC and ended at 11:45. The event was associated with a Type II Radio Emission at 11:23 UTC, with an estimated...... Read more

A strong volcanic tremor and new heating cycle started at Mt. Ruapehu's Crater Lake two weeks ago. On March 28, 2022, GeoNet raised the Aviation Color Code to Yellow. The Volcanic Alert Level remains at Level 2 since March 21. Ruapehus Crater Lake (Te Wai...... Read more

The Philippine Institute of Volcanology and Seismology (PHIVOLS) has raised the alert status of Taal volcano from Alert Level 2 (increasing unrest) to Alert Level 3 (magmatic unrest) after a phreatomagmatic eruption at 23:22 UTC on March 25, 2022 (07:22 LT, March...... Read more

A moderately strong solar flare measuring M1.4 at its peak erupted from Active Region 2974 at 05:26 UTC on March 25, 2022. The event started at 05:02 and ended at 05:50 UTC. The eruption was associated with a Type II Radio emission at 05:14 UTC, with an estimated...... Read more

Indonesia's Anak Krakatau volcano started erupting again early March 24, 2022, ejecting ash up to 1 157 m (3 800 feet) above sea level at 04:10 UTC. The observed ash column was white to gray with thick intensity towards the south. The country's Center for...... Read more

New activity/unrest was reported for 4 volcanoes from March 16 to 22, 2022. During the same period, ongoing activity was reported for 20 volcanoes. New activity/unrest: Bezymianny, Central Kamchatka (Russia) | Lonquimay, Central Chile | Manam, Northeast of New...... Read more

Increased seismicity detected under Chile's Lonquimay volcano since March 9, 2022, prompted SERNAGEOMIN to raise the Alert Level for the volcano from Green to Yellow on March 21, 2022. The last eruptive episode of this volcano lasted from 1988 to 1990 (VEI 3)....... Read more

A destructive wedge tornado ripped through parts of New Orleans, Louisiana Tuesday night, March 22, 2022, causing extensive damage, killing at least one person, and leaving several others injured. This raised the number of fatalities related to the severe weather...... Read more

Seismic activity at Manadas volcanic fissure system in the NW part of So Jorge Island, Azores, Portugal continues at a high level for the fourth day in a row. The Civil Protection of Azores is preparing preventive measures in case of a strong earthquake or...... Read more

A very strong earthquake registered by the USGS as M6.6 hit near the eastern coast of Taiwan at 17:41 UTC on March 22, 2022. The agency is reporting a depth of 10 km (6.2 miles). EMSC is reporting it as M6.7 at a depth of 30 km (18 miles). The epicenter was located...... Read more

Several destructive tornadoes ripped through parts of Texas and Oklahoma on March 21 and 22, 2022, during a violent severe weather outbreak that's now shifting east. One person was killed and more than a dozen injured. The Storm Prediction Center has so far...... Read more

A very strong earthquake registered by the USGS as M6.7 hit northern Mid-Atlantic Ridge at 16:35 UTC on March 22, 2022. The agency is reporting a depth of 10 km (6.2 miles). EMSC is reporting M6.3 at a depth of 10 km. The epicenter was located about 1 173 km (730...... Read more

I got lazy for a few years but Im back! Actually the gas furnace going out forced my hand but..These nice people stopped by and for about 10 grand theyll install another one, lol. Im going to rip that old one out and ponder my options. 10 grand for Petes sake! Lol.

Blockchains transparency and traceability can aid sustainability and reduce carbon emissions for climate change.

And that was just a warm up on match day for the Elon University womens lacrosse team.

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Dr. Daniel Amen sounds off on Unfiltered after WSJ op-ed says intense politics are fueling childhood depression. #unfiltered #foxnews

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Artist Paints Architectural Portraits Onto Concrete Fragments of Same Demolished Estate

Sometimes the choice of materials is just as meaningful as the art itself. Artist Harriet Mena Hill has been working on an ongoing series of unorthodox paintings called The Aylesbury Fragments, rendering scenes of architecture directly onto pieces of concrete. Each of these remnants is salvaged material from the Aylesbury Estate, a large housing complex in South East London, which is being demolished as part of a regeneration program.

Hill finds a way to record snippets of the dismantled buildings on numerous shards of concrete, which range from palm-sized to nearly the length of a human torso. The inspiration for what she paints derives from the stories of residents who used to live in these torn-down apartments. I started making work about the Aylesbury Estate in response to my experience of working with the residents on art projects back in 2018, Hill tells My Modern Met. The Aylesbury Fragments document what remains of the occupied parts of the estate as it undergoes regeneration. The concrete pieces that Hill uses come from a block of flats called Chiltern which was demolished in 2020.

The Aylesbury Estate was designed by architect Hans Peter Fenton and constructed between 1963 and 1977. It consisted of 2,700 dwellings that housed about 10,000 residents at one time. During the 1980s, however, the site went through a period of disrepair, eventually prompting the beginning of a regeneration program in 2005. I wanted to present the human and community side of the estate which has historically experienced an extremely negative portrayal in the press, Hill explains. The works offer an opportunity to do so.

Scroll down to see more works from this series, and follow Hill on Instagram to keep up to date with her latest projects.

Artist Harriet Mena Hill paints detailed scenes on pieces of concrete.

...

Bitcoin bulls have a lot to do preserve newly-won support, but failure to do so could still see a BTC price cascade below $20,000, research warns.

hot diggity submitted a new resource:

1867/77 Werndl rifle disassembly/reassembly - 1867/77 Werndl dasassembly/reassembly

Read more about this resource...

A War doesnt have to be publicly declared or mutually agreed upon by both of the participants. The United States should be keenly aware of this, considering our corporeal and civic annihilation of Syria, Iraq, Afghanistan and Libya to name a few. Would any of these countries agree to be bitch-slapped back into a feudal age if they couldve avoided it?

The authoritarian regime in China has engaged in a subversive war on the American citizenry, whether the Biden administration will admit to this or not. Is Biden reluctant to address Chinas complicity in the fatal poisoning of U.S. civilians because hes colluded with the corrupt nation so often?

Chinas unrelenting assault on young Americans with copious amounts of fentanyl has eradicated tens of thousands in recent years. Biden refuses to return volley for this attack and has aided in its efficiency by recklessly opening our borders. In comparison, the Bush regime slaughtered millions in recompense for the murder of just three-thousand on 9/11, most of which were unwitting, Middle Eastern dirt-farmers.

Apart from poisoning thousands of remiss young adults and irrevocably destabilizing their families, the Chinese have been purchasing land around key American military installations.

As disturbing as a communist land grab surrounding American military bases might appear, it pales in comparison to other occurrences. Recently, Chinese surveillance operations have been acknowledged to exist in several of our citys.

These surveillance hubs are littered throughout the densely populated areas of communist China and they infect every nook and cranny of its society. It seems unfathomable, however, to imagine these subversive intelligence agencies operating in the United States. If American citizens are privy to this alarming development, then its safe to say that our officials mustve known for years.

The Chi-com infiltration of our cities and around our military bases is only astounding when taken out of context. The reality is that we are voluntarily tied at the hip with Chinas oppressive regime.

Just take a stroll to the nearest bargain superstore and youll discover 99% of its products are made in China. Is there any other time in history when the United States was so interdependent with such a formidable enemy?

What about uber-wealthy Americans like Lebron James?

Prescott Bush, the patriarch of the murderous Bush clan, was documented to be a Nazi sympathizer and was fiscally invested with them well after we declared war on Germany. This begs t.........

As we learn more and more that money is fake, shouldn't we ask ourselves why we're willing to trade real, hard, honest work for fake money.

If the money is fake, shouldn't the work be fake?

Then, if the answer to that question is 'yes', then we must ask ourselves....

What does fake work look like?

To answer my own question, I guess it looks like a youtube video, or a tik tok video, or a government official asking the Federal Reserve for a billion dollars.

Then we should ask ourselves,...

work....

Post your favorite Motivational Posters here.

_

More to share with your friends, from the New York Post no less: In the past few weeks, a series of analyses published by highly respected researchers have exposed a truth about public health officials during COVID: Much of the time, they were wrong. To be clear, public health officials were not wrong for making recommendations based on what was known at the time. Thats understandable. You go with the data you have. No, they were wrong because they refused to change their directives in the face of new evidence. When a study did not support their policies, they dismissed it and censored opposing opinions. At the same time, the Centers for Disease Control and Prevention weaponized research itself by putting out its own flawed studies in its own non-peer-reviewed medical journal, MMWR. In the final analysis, public health officials actively propagated misinformation that ruined lives and forever damaged public trust in the medical profession. Here are 10 ways they misled Americans:

Misinformation #1: Natural immunity offers little protection compared to vaccinated immunity

A Lancet study looked at 65 major studies in 19 countries on natural immunity. The researchers concluded that natural immunity was at least as effective as the primary COVID vaccine series.

Here is a reminder of the remote healing sessions and the full Moon meditations between March 5th and 7 th, as well as the monthly Divine Intervention Meditation on Tuesday, March 7th at 12:40 PM UTC.

Monthly International Ascended Masters and Stellar Healing Rays Remote Healing Sessions Every full Moon, the International Golden Age Group and Prepare For Change Japan Official offer remote healing sessions that can help people around the world to heal their inner being and mind. This is a gift to everyone and is free of charge. https://www.welovemassmeditation.com/2018/08/monthly-ascended-masters-and-stellar.html   For the upcoming full Moon, three international remote healing sessions will be held at the time listed below: First Day: Sunday, March 5th from 2 PM to 2:30 PM UTC https://www.timeanddate.com/worldclock/fixedtime.html?msg=%5BFirst+Day%5D+Monthly+Ascended+Masters+and+Stellar+Healing+Rays+Remote+Healing+on+March+5th&iso=20230305T14&p1=1440&am=30

Link: https://www.youtube.com/live/G0UIRaeP2V8

  Second Day: Monday, March 6th from 2 PM to 2:30 PM UTC https://www.timeanddate.com/worldclock/fixedtime.html?msg=%5BSecond+Day%5D+Monthly+Ascended+Masters+and+Stellar+Healing+Rays+Remote+Healing+on+March+6th&iso=20230306T14&p1=1440&am=30 Link: https://www.youtube.com/live/w9fI7cJ2Www   Third Day: Tuesday, March 7th from 2 PM to 2:30 PM UTC https://www.timeanddate.com/worldcloc...

It was George Washington who said "Peace Through Strength" and later Ronald Reagan reiterated this policy "Peace Through Strength" and followed through with building up our military.
We now have the Bidumb administration who has taken a u-turn from this effective policy.
We are not ready for war
1. "Strategic Oil Reserves" are at an all time low,
2. We now have a shortage of missiles
3. Military recruitment is down 30%
4. Retention of career military staff all time low
5. Military...

Is the USA ready for War

have had a gum/tooth/sinus infection for some time with spitting up pink saliva in the morning and a swollen glade just behind jaw now and have taken clindamycin and finally a z-pac I finished last night around 5pm. got up this morning and spit was a rather bright red looked at tongue in mirror and ugh... did not think to take pictures till after the 3 morning rinses tried tooth brush on it and so far don't want to come off... finished zpac last night around 5 pm... no idea what this is can...

WTF is this

Researching more than 100 bitcoin mining companies, its clear that this industry is poised to advance energy consumption more than any other.

This is an opinion editorial by Ritabrata Santra, an engineer focused on energy tech.

I bought my first bitcoin in 2016. I was a college sophomore and it was my second year living in the U.S. As I was acclimating myself to the new way of life I found myself living, I came across an article on Bitcoin.

I had saved up some money from my on-campus jobs. As someone who saw the devaluation of my parents hard-earned money, the value proposition of Bitcoin was immediately clear to me and I made the second-biggest mistake of my life: I bought a bitcoin off of Coinbase (for $1,500) instead of mining and cold storing (HODLing) it! If you are wondering what my biggest mistake is: Two months later, I got an internship in Germany, so I sold the bitcoin to buy myself a ticket to Berlin, and six months later, one bitcoin was worth around $16,000!

The Energy Trilemma And Bitcoin

One of the many things that stood out in my new way of life in the U.S. is the reliable access to electricity. Growing up in India, I witnessed how a lack of energy impacted health, knowledge and opportunity.

Today, developed economies consume as much energy as 12 times the average in some of the developing economies. There are over 900 million people who do not have access to electricity but we flare enough gas every year to power entire sub-saharan Africa. In other words, we burn enough gas (emitting carbon dioxide, or CO2) to provide energy for millions of people without creating any economic value, as we do not have the necessary technology to profitably transport the energy where it is most needed.

I believe that the energy trilemma, the need to balance energy reliability, affordability and sustainability, is one of the great challenges of our lifetime we need to eradicate energy poverty and meet the additional demand of energy from emerging economies, while actively decarbonizing to reach carbon neutrality.

Bitcoin mining serves as a medium for capturing the wasted economic potential of excess energy resources, accelerates otherwise expensive but innovative renewable development, and therefore sits at the center of solving the energy trilemma.

...

12ft | How the Biggest Fraud in German History Unravelled | The New Yorker

Longish, but a well written piece on the "fraud hiding in plain sight'.

massive fraud.

WHO Treaty will usurp state and national laws, impose draconian lockdowns and allow for local law enforcement to put you into concentration camps if you don't take the next vaccine:

See 2:40 of this video to learn about the WHO treaty:
Situation Update, Mar 3, 2023 - WHO "treaty" to assert global medical DICTATORSHIP over all nations and states

Please contact state representatives and tell them to not support the...

WHO Treaty

On this episode, Trey is joined by Speaker Kevin McCarthy, to discuss his newly appointed role as House Speaker.

Speaker McCarthy emphasizes his commitment to working across the aisle to benefit the American people. He also shares his thoughts on this past Januarys contentious House Speaker election and his previous run for the Speaker position. 

Later, Trey and Speaker McCarthy reflect on their friendship and time serving in Congress together.

Follow Trey on Twitter: @TGowdySC

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This post contains an exchange between myself and Ravi Chandirimani, then the editor of CYPN. It dates from May 2009. He advised those involved in IDYW to embrace pragmatism. Being pragmatic has certainly done him no harm. He sits today on the Mark Allen Board of Directors. Fair enough. Does the success of his individual pragmatism expose the naive preciousness of the collective, that was the IDYW? Or, ironically, given the failure of IDYW to organise a successful resistance to the behavioural capture of youth work, what has been the price of the victory of Ravis pragmatic advice?

The links in the following paragraph do not work. Evidently, CYPN and its owners, the market-leading brand, Mark Allen Holdings dont do history.

The debate about youth work values and core principles continues on the pages of Children and Young People Now In the article Are government policies chipping away at youth work values? Janaki Mahadevan collects together the views of a panel of experts. Now being dubbed an expert does my head in, but well leave this contemporary obsession with experts to another day. Whilst in a related Opinion piece ...

Are you experiencing frequent headaches and blurred vision? These symptoms could be related to your vision, but did you know that you can improve it by eating the right foods?

In addition to genetics and aging, factors such as poor diet and overexertion can contribute to vision problems. To help you maintain good eye health, weve compiled a list of 7 foods high in lutein, a nutrient essential for proper eye function.

From lettuce to arugula, these leafy greens are packed with vitamins, minerals, and natural antioxidants in addition to lutein. Incorporating them into your daily meals is easy and has no contraindications.

So, if you want to take care of your eyesight, be sure to add these vegetables to your diet! Let us know in the comments if you already knew about the benefits of these foods.

-

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Disclaimer: The materials and the information contained on Natural Cures channel are provided for general and educational purposes only and do not constitute any legal, medical or other professional advice on any subject matter. These statements have not been evaluated by the FDA and are not intended to diagnose, treat or cure any disease. Always seek the advice of your physician or other qualified health provider prior to starting any new diet or treatment and with any questions you may have regarding a medical condition. If you have or suspect that you have a medical problem, promptly contact your health care provider.

Brian Kilmeade torches Garland, Biden, congressional Democrats on One Nation with Brian Kilmeade. #onenation #foxnews

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Following the temporary suspension from Ukraines central bank, crypto exchanges like Binance and Kuna made official announcements informing investors about the inconvenience.

A funny clip of NBC 12 anchor Eric Phillips has cropped up again six years after this funny but embarrassing on-air gaffe.

u/zephyr-zoos post on r/funny brought the funny fail to the attention of a new audience, who had some great reactions.

I mean, hes right, if you got anything looking like rice or something that came from a slow cooker in there, take action!
u/Ennurous

To be fair, Id be doubly alarmed if my panties were being recalled for risk of fire or electric shock.
JackOLoser

I love the calm correction. Hmm that doesnt seem right.
Spilly_Talent

No rice cooker in mine.
matttttj

Dont get your pantries in a bunch, yo.
cawdel

It took me listening to it a couple times to realize he said its supposed to be PANTRIES because to me it sounded like he said pants strings.
GratefulPhish42024-7

GOD DAMN these electric sex panties!
LupinThe8th

TIL rice or slow cookers in your panties can cause fire or electric shock. Good to know.
RyansBooze

u/rocketneo pointed out that it could have been worse.

Well, I mean, better than Go fuck yourself, San Diego.

READ MORE

You can see the moment this Portuguese newsreader spots her massive error

Source News Bloopers H/T r/funny Image Screengrab

The post...

Texas residents shared if theyd noticed an increase in pet food prices and whether the commodity could ever get so pricey that theyd have to give up their pet.
#foxnews #foxnewsdigital

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Watch more Fox News Video: http://video.foxnews.com
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FOX News Channel (FNC) is a 24-hour all-encompassing news service delivering breaking news as well as political and business news. The number one network in cable, FNC has been the most-watched television news channel for 18 consecutive years. According to a 2020 Brand Keys Consumer Loyalty Engagement Index report, FOX News is the top brand in the country for morning and evening news coverage. A 2019 Suffolk University poll named FOX News as the most trusted source for television news or commentary, while a 2019 Brand Keys Emotion Engagement Analysis survey found that FOX News was the most trusted cable news brand. A 2017 Gallup/Knight Foundation survey also found that among Americans who could name an objective news source, FOX News was the top-cited outlet. Owned by FOX Corporation, FNC is available in nearly 90 million homes and dominates the cable news landscape, routinely notching the top ten programs in the genre.

Watch full episodes of your favorite shows
The Five: http://video.foxnews.com/playlist/longform-the-five/
Special Report with Bret Baier: http://video.foxnews.com/playlist/longform-special-report/
Fox News Primetime: https://video.foxnews.com/playlist/on-air-fox-news-primetime/
Tucker Carlson Tonight: http://video.foxnews.com/playlist/longform-tucker-carlson-tonight/
Hannity: http://video.foxnews.com/playlist/longform-hannity/
The Ingraham Angle: http://video.foxnews.com/playlist/longform-the-ingraham-angle/
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Brazilian Instagram user Thiago @JackBauerDF has given his followers, and everyone else, an insight into what its like to be owned by a cat.

His face speaks volumes.

...

Over in Sydney, late-night radio hosts Kyle and Jackie O recognised a problem weve all faced at one time or another not knowing the name of someone you really should know the name of.

Maybe you werent listening when they were introduced or simply forgot immediately afterwards. It happens.

It turns out that there are actual tips for getting around that problem.

Not all tips are created equal.

@_j.o.h.h_ #name #whatsyournane #whoareyou original sound New Videos Every Day

Technically, thats three discreet ways to find out and one thats just bang on, but hey lets not split hairs.

The clip isnt new, but it was new to these people and they had one or two things to say about it.

Lets hope its not Ben sends in Pat
B.

Take them to Starbucks
ZuluPrincess

Wats ur instagram handle oh its just my name then 27
Leah

Ways not to be obvious: just ask for their name
RandomPerson

With Pat, after he spelled it she should have said no i asked you to spell it, I T to save herself.
...

Jean Charles Moyen, a French-Canadian film maker, has just revealed several spontaneous teleportation experiences he had in December 2022 where he witnessed space arks inside of Mount Fuji, Japan and Mauna Kea, Hawaii. In both cases, he encountered beings guarding the space arks, which are closely associated with the fire energies of the two volcanoes. []

Recent revelations have confirmed what many of us knew all along-  COVID came from a lab in China.  I am agnostic as to whether it was created as a bioweapon or it emerged from a simple, but devastating error. Either way, China is trying to absolve themselves of all responsibility for unleashing this deadly virus around the world. Thanks to their actions, []

The post Science Based Satire: We Should Repeatedly Expose Unvaccinated Children to a Novel Virus That Came From a Lab in China. first appeared on Science-Based Medicine.

TEMPE, Ariz. 90s alt rockers Gin Blossoms finally acknowledged their white privilege that enabled them to drive around this town being chased by the cops without any repercussions, confused and old listeners of Sirius XMs Lithium confirmed.

Anyone whos heard our music is well aware of our extreme level of whiteness. Heck, were routinely ranked between Savage Garden and Toad the Wet Sprocket as the most likely to sunburn indoors rock groups of the 90s. But we didnt learn until recently about the privilege that comes along with being the alt rock equivalent of mayonnaise on Wonder Bread, explained bassist Bill Leen. Its important now that we recognize that not every band could spend the day letting the cops chase them without facing arrest, or worse. Lets just say if it was Living Colour in that situation, the song Hey Jealousy would have ended very differently.

Random Tempe woman commuting to work Shawna Howard described a related run-in with Leen.

I saw this middle-aged white guy walking down the street and briefly stopping and speaking to every person of color. When he reached me, he said Im sorry. I asked for what and then he explained hes in the Gin Blossoms. I got excited thinking they were the guys who wrote that song from The Babysitters Club movie but apparently that was Better Than Ezra? said Howard. I suppose I appreciate what hes trying to do, even if it may negatively affect his career. Because lets face it, bands like his mostly play midwestern state fairs, and those places are teeming with corn dog-eating, anti-woke white people.

Former MTV VJ and 90s rock scene staple Matt Pinfield elaborated on this emerging trend among aging rock bands.

The one consistent throughline in the story of grunge and alternative rock is white privilege. I mean, how else could a band like Matchbox Twenty receive a record contract and radio play without it, said Pinfield. But Zoomers that are now discovering this music are viewing these lyrics through a different lens than their parents. First, consider the so-called dark secret behind the boathouse in The Toadies Possum Kingdom. And its probably best to just avoid the thorny issue that is King Missiles Detachable Penis.

In response to Gin Blossoms newly found empathy and atonement, Stephan Jenkins of Third Eye Blind has vowed to continue being the biggest asshole of 90s rock.

The post Gin Blossoms Finally Acknowledge White Privilege of Letting Cops Chase You Around and Facing Zero Repercussions appeared first on The Hard Times.

Each week The Hard Times travels back to review an album that we probably should have when it came out. This week were looking at Radioheads iconic Kid A.

Ah, yes. Radiohead. The Reel Big Fish of electronica. The Limp Bizkit of experimental music. The Taylor Swift of art rock. A lot of things could be said about this band. Especially this critically acclaimed record.

I remember the first time I ever heard Kid A way back in the early 2000s. I had just downloaded a copy from the file-sharing behemoth known as LimeWire. If you dont remember, LimeWire was like Spotify but totally illegal because artists didnt get any money from it. Unlike Spotify where they at least get spare change here and there.

Anyway, this album was my very first introduction to the Head, and boy was I floored. The first Kid A track I downloaded was an MP3 of their song Creep. Simply incredible vibes. Next, I got M4As of Karma Police and High and Dry. Im telling you, it was such a mind-blowing start to a piece of work that it almost sounded like it could be a greatest hits album.

From there, Kid A kind of took a turn. The next songs that I downloaded were MmmBop, Enter Sandman, and Mambo No. 5. I had heard this band got pretty experimental but I was not expecting this kind of range.

At one point it sounded like I was listening to seven or eight different bands on one album. That being said, I think my favorite Radiohead song of all time is definitely Wu-Tang Clan Aint Nuthing to F With. Thats track 24 on the album. Not enough experimental art rock bands incorporate hip-hop into their sound.

This album is an absolute classic and quite possibly the most experimental record of all time. If youre a Radiohead fan, you know exactly what Im talking about already. Its just too bad LimeWire had to shut down due to the rampant copyright infringement because I never wouldve found the classic song Smells_Like_TeenSpirit by Third Eye Blind without them.

Score: Kid A+

BRUNSWICK, Maine Determined punk Leroy Ainsley decided to throw caution to the wind recently when he attempted to pull off wearing white jeans, sources confirmed amid derisive snickering.

Ill be the first to admit I was nervous to take such a big swing. Every pair of jeans Ive ever worn has been a dark blue or black, so it was going to be jarring no matter what. But I figured Id be able to make them work, said Ainsley while holding his head in his hands for several consecutive minutes. Lets just say, I was ripped to shreds the minute I stepped outside. I thought I lived in a warm, supportive community, but apparently I live on the dais of a Comedy Central Roast. Never again.

Brunswick residents of all walks were reportedly ruthless in their impromptu mockery.

I couldnt stop laughing. I mean, you could tell the little weiner was on the fence in trying them out in the first place, you could practically smell it on him. The guy had no confidence whatsoever, so I had to let him have it, said Ainsleys postal worker Helena Radscombe. Ugh, just picturing it turns my stomachwho does he think he is, fuckin Andrew W.K.? You know how people throw red paint on people in fur coats? We gotta start saving a few cans for timid bozos giving new pants a whirl. Yuck!

Denim Depot salesperson Irv Gladstone revealed that white jeans are something of an inside joke in the apparel parlance.

Ill admit, I sold the young man the jeans in question, and I dont regret it. The entire industry is corrupt when it comes to white dungarees, its an open secret, said Gladstone, nervously puffing on a cigarette. So when a rube comes in off the street wanting something fresh, we pounce. Let that be a lesson to your readers out there: never, ever try something new. Scientifically, no one can pull off white jeans unless they live in a tropical climate and are over the age of 55. But luckily for us denim salesmen, Florida exists.

At press time, Ainsley lamented that hell never have to worry about wearing jeans of any variety ever again, as the local bullies wont stop pantsing him as soon as he leaves his house.

The post White Jeans Attempted appeared first on The Hard Times.

Like many of you, I used to sit in my drab apartment and dream of moving to Europe, the land of affordable train travel, relaxed attitudes towards casual nudity, and rampant alcoholism. Well, friends, Ive cracked the code.

Keep reading to learn how I moved to Sweden for at least the next 3-5 years. Maybe longer if I play my cards right.

It was a simple trick really. I just committed a string of felonies, or grov frbrytelses as theyre known in these parts. All I had to do was fall in with a gang of Swedish criminals and embark on a crime wave that landed me right here in Gothenburgs own Hrlanda Park prison!

My cell features 1 bedroom, 1 bathroom, a bespoke dining room set, and modern light fixtures. It also contains artwork crafted by local artisans. Furthermore, I was welcomed to the block by my neighbor, a famous bank robber named Henrik The Swedish Swindler Berg, who made me a wonderful dinner with fresh fish, dill potatoes, and lingonberry-coated meatballs.

Needless to say, this is a serious upgrade over my old apartment.

For starters, I would pay at least $2,500 a month for something like this in any major American City, and thats not counting HOA fees. And since Sweden offers free higher education to all incarcerated (and non-incarcerated) residents I figure I might as well complete that marketing degree I never finished. I considered taking some Swedish classes too, but they speak better English here than anywhere else in the world, so why bother?

Sure I miss my friends and family back home, but you have to leave the nest sometime dont you? Besides, my mom always dreamed that I would one day live in a safe neighborhood with no guns, promising career prospects, and low crime rates.

She just never thought that place would be a Swedish prison.

The post How I Upgraded My Life by Committing a Crime in Sweden and Going to One of Their Nice Ass Prisons appeared first on The Hard Times.

Chatcasso won first prize in the BNB Chain hackathon for its AI-powered NFT creation tool.

Monetary policy for cryptocurrencies is a game-changer with fixed supplies and decentralized control, they challenge traditional monetary policy tools.

Hershey's faces backlash over putting trans woman on candy bar wrapper for International Womens Day

"The chololate's out of the wrapper!" --Fae Johnstone

I've never been a big fan of hersheys chocolate, but now I'll have the above quote in my head every time I see...

Another once great company goes woke - Hersheys

White Guy Makes A Really Bad Black Joke

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A forum isn't complete without a listening thread. I'll start.

D-A-D - Jihad

Ripples CEO Brad Garlinghouse said the SECs lawsuit against Ripple is the regulator playing offense and attacking the industry as a whole.

An autistic Year 10 (or equivalent to Grade 9 in the US) student from Wakefield, England, was dismissed from his school and bombarded with death threats after an event where a Quran was allegedly disrespected.

Boy who 'dropped a copy of the Quran at UK school' receives death threats https://t.co/ZosIO4hBH9

Daily Mail Online (@MailOnline) March 2, 2023

The incident started with a wager after the unnamed 14-year-old student played Call of Duty with his friends. The winner could tell the loser what to buy or do. In this case, the autistic student lost the wage and was told to buy a copy of the Quran. He complied and purchased the holy book from Amazon.

The autistic student then brought the Quran inside the premises of Kettlethorpe High School and gave it to another student, who recited a passage from the book to other students on a tennis court. It was also revealed that an unrelated boy knocked the Quran off the students hands, causing it to fall on the floor.

Afterward, the autistic student picked up the Quran and placed it in his bag. Soon after, rumors quickly spread that the Quran was thrown around, spat at, and even burned. They were refuted by Akef Akbar, an independent Muslim councilor for East Wakefield, who posted photos of the Quran on Instagram with a caption narrating the incident.

Police record "hate incident" after autistic boy drops Quran in busy school corridor - as four pupils suspended over false rumour that it was set alighthttps://t.co/nFGOL74lVM

LBC (@LBC) March 1, 2023

Four students were suspended for a week since they were believed to have crossed the line. The local community set up a meeting to discuss the events that occurred and to put the citys Muslim community at ease. The assembly happened at Jamia Masjid Swafia, a mosque in Wakefield.

People who participated in the meeting include Imam Hafiz Muhammad Mateen Anwar, Inspector Glen Costello, Chief Inspector Andy Thornton, Kettlethrope High School headteacher Tudor Griff...

An article from the British online magazine Spiked revealed that a private liberal arts college in Minnesota temporarily closed and censored an art exhibition of a feminist artist after claiming some Muslim students were offended by it.

I wrote at @TheFIREorg about "non-consensual" art at Macalester College, blasphemy, and the foolishness of letting people decide what expression others, not just themselves, should be able to look at. https://t.co/vGaxGX23M2

Sarah McLaughlin (@sarahemclaugh) February 10, 2023

The exhibition opened at Macalester College in St.Paul last January 27. It featured the works of Taravat Talepasand, a 44-year-old Iranian-American female artist originally hailing from Oregon. Her works often challenged political and religious orthodoxy, criticizing Islamic conservatism and the oppression of women under Islamist regimes.

Some artworks the college claimed to have shocked and offended students' sensibilities include a risqu drawing of a woman in hijab lifting her clothes and showing her underwear and another lifting her niqab to reveal her underwear while raising the middle finger.

The exhibit also featured porcelain sculptures of women in niqabs revealing their breasts. Lastly, Talepasand also featured a neon sign saying Woman, Life, Freedom in English and Persian. This slogan has become a symbol of protest against the Islamic Republic after protests broke out last year.

Not pleased with her artworks, some Macalesters student body members submitted a petition demanding to shut down the exhibition, claiming that Talepasands works caused "deep pain" and even perpetuated harm against Muslims.

I notice a lot of similarities between the language used by the complaining parties here and those used at Hamline. Unfortunately people are learning that using a particular framing and the right words will allow them to get their way even if it means censoring others.

Daniel Erdle (@DanielErdle) February 11, 2023

...

A cube-shaped megastructure for Riyadh in Saudi Arabia sparks controversy in social media for its similarity to the 'Kaaba.'

On February 16th, Saudi Arabia lifted the curtain on the latest architectural design of a cubic-shaped megastructure, which received criticism for strikingly resembling Islam's most sacred site, the Kaaba.

A gateway to another world: #TheMukaab will be the worlds first immersive, experiential destination. Large enough to hold 20 Empire State Buildings, the global icon will feature innovative technologies to transport you to new worlds.#NewMurabbahttps://t.co/5R4DqQdPyS pic.twitter.com/vr9M8cTI1I

Public Investment Fund (@PIF_en) February 16, 2023

According to the Saudi kingdom's Public Investment Fund (PIF), the construction of "The Mukaab" - derived from the Arabic word for the cube- will occur in Saudi Arabia's capital Riyadh and is expected to be completed by the end of this decade.

The height, width, and length of this massive city-within-a-city will be 400 meters which is large enough to contain at least 20 Empire State Buildings. Providing over 100,000 residential units, 9,000 hotel rooms, and 1.4 million square meters of office space, it will also be the home to many entertainment and culture venues.

Spearheaded by Crown Prince Muhammad bin Salman, this project is one of the plans to create the biggest and most advanced downtown in the world in Riyadh.

Inspired by the styles used in the Najd region in Saudi Arabia for the design and architecture, the building features overlapping triangular forms. However, some social media users have pointed out that the design is far too similar to the Kabba.

The Kabba is a cube structure at the center of Islam's most important mosque, Masjid al-Haram, in Mecca. The Muslims consider it the House of God and the Qibla (direction of prayer) when performing Namaz.

One Twitter user named Kariman said, "This is a strange choice, or is it just me? The New Mukaab, like the Kaaba but with shopping venues...?"

...

A writ petition was filed in the Madras High Court by a 23-year-old woman who alleged that she fled her home in Madhya Pradesh because her stepmother was planning to kill her as a part of a human sacrifice ritual. She also claimed that her younger brother was killed in a past ritual.

[Human Sacrifice] Woman From Madhya Pradesh Approaches Madras High Court Seeking Police Protection Against Family Members @UpasanaSajeev #MadrasHighCourt #HumanSacrifice https://t.co/HB8TvQezRG

Live Law (@LiveLawIndia) February 23, 2023

Alongside Advocate S. Doraisamy and V. Elangovan, the petitioner appeared in court and said her friends helped her escape to Tamil Nadu for her safety.

In the affidavit she filed, the petitioner said that Uttar Pradesh was her birthplace; however, she later moved to Madhya Pradesh with her family. She also said that her father worked in the Agricultural Department but retired in 2017.

She was a student of Government Maharani Laskshmibai Girls' College in Bhopal and said that she held a Master's degree in nutrition and dietetics. Currently, she is pursuing a diploma in Yoga. She claimed that her parents forced her to become a member of the Akhil Bharatiya Vidyarthi Parishad (ABVP), a right-wing all-India student organization. However, she also said that she left the organization after a while.

The petitioner allegedly accused her stepmother and other relatives of being followers of black magic after coincidentally learning about their intention to kill her to perform a human sacrifice ritual. She also heard about her younger brother's demise, who underwent the same ritual when he was only ten.

Will extend police protection to MP woman claiming that parents plan to 'sacrifice' her: State to Madras High Court

report by @ayeshaarvind http...

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Starting from Seed: What You Need and How Do You Do It

I'm not saying the AR15 is the alpha and the omega of guns. The best survival gun depends on your location. If semiautos are banned where you are that kind of puts a damper on things. The best game getting guns are likely a 22lr, a shotgun or big bolt action rifle depending on where you are.
But there's a reason why the government uses them, politicians want to take them and mom's looking for action want to ban them. Plus after it hits the fan there's going to be a lot of them laying about....

AR15 hit piece fail.

I hop in and read a bit as I can. Things with Mrs Krap have gone down hill quite a bit. Thought things were going kind of OK today and then her Blood Pressure crashed to 40/32. She was pretty much passed out when we flew into the ER entrance. Spent from around 1pm-8pm getting her BP up and somewhat stable at 74/42 and checked her into the ICU. Not much I can do sitting there and I am more in the way than anything. So I came back home to take care of the dogs and worry. They sedated her...

Just checking in.

Gentrification brings a lot of mixed emotions to the surface.

And that includes people on both sides of the issue.

So was this person an a**hole for what they said to their new neighbors that clearly have a lot of money?

Get all the details below.

AITA for telling the new neighbors that they got what they paid for, including being shunned by the neighborhood?

Where I live, real estate developers have started snatching up family homes, bulldozing them and building enormous 2 million dollar houses on the plots of land. The houses also stick out horribly in terms of aesthetics think single level brick homes with a 3-level gigantic white and black box in the middle.

My homes been in my family for several generations. We have always been known for having a large, beautiful garden. We invited over kids to help with gardening, we gave away so many veggies, wed hold parties, etc. Its been a neighborhood treasure for years.

Until developers snatched up the lot next door, bulldozed and erected an enormous house that blocked out the light to most of the garden. Many of us tried to fight it with the city but everything was denied. It was heartbreaking. Our neighborhood has been changed forever. This was a link to my family and I almost have had to go through a grieving process for it.

The new owners moved in and were not welcomed warmly by people in the neighborhood. I avoided them for as long as I could, other than politely waving or nodding. It was a young couple in their early 20s.

We finally came face to face and the woman asked if we could chat. She said that they felt like maybe theyd done something wrong when they moved in, or if they arent pulling in their trash bins or something, being too loud, etc, because people havent bee...

A MetaMask security analyst said the rumor was the 2023 adaptation of attempted market manipulation.

PMID:  Struct Chem. 2022 Jun 16:1-16. Epub 2022 Jun 16. PMID: 35729937 Abstract Title:  Study of nonlinear optical responses of phytochemicals ofby quantum mechanical approach and investigation of their anti-Alzheimer activity with in silico approach. Abstract:  UNLABELLED: is a flowering plant with promising medicinal plants with a wide variety of active phytochemicals. The present study aimed at the computational investigation of the nonlinear optical (NLO) responses of the active phytochemicals of theThe computational investigation of the NLO features was done by using the density functional theory (DFT) by B3LYP/6-311G++(d, p) basis set. The structural parameters, mulliken charge distribution, and molecular electrostatic potential (MEP) surface clearly show the intramolecular charge transfer within Clitorin. The NLO properties were identified by computing the polarizability parameters. As the plant has high medicinal characteristics, the inhibiting properties of its phytochemicals were also investigated to combat Alzheimer disease (AD). The systematic in silico study identifies Clitorin as the most active and inhibiting phytochemicals of the plant. The results obtained from molecular dynamics (MD) simulation tell the stability of the complex and make it a fair selection as a drug-like molecule against AD. The cardio-toxicity analysis done for the Clitorin molecule verifies that it is harmless for the supplementary material available at 10.1007/s11224-022-01981-5.

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PMID:  Access Microbiol. 2022 ;4(4):000343. Epub 2022 Apr 26. PMID: 35812712 Abstract Title:  Antibiofilm properties offlower anthocyanin-rich fraction towards. Abstract:  In Asia,flowers are commonly used as a traditional medicinal herb and as a food colourant. Their bioactive compounds have anti-inflammatory, anti-microbial and anti-biofilm activities.is one of the major pathogens that cause biofilm-associated infections resulting in an increase in antimicrobial resistance. Hence, the aim of this study was to investigate if the anti-biofilm properties of the anthocyanin-rich fraction offlowers were effective against. The effect of the anthocyanin-rich fraction offlowers onbiofilms formed on a polystyrene surface was determined using the crystal violet assay and scanning electron microscopy (SEM). The anthocyanin-rich fraction reduced biofilm formation by fourstrains with a minimum biofilm inhibitory concentration value ranging between 0.625 and 5.0mgml. We further show that the biofilm-inhibiting activity offlowers is not due to the flavonols but is instead attributed to the anthocyanins, which had significant biofilm inhibitory activity (64.01.1%) at 24h in a time-response study. The anthocyanin-rich fraction also significantly reduced bacterial attachment on the polystyrene by 1.1 log c.f.u. cmsurface based on SEM analysis. Hence, anthocyanins fromflowers have potential as an agent to decrease the risk of biofilm-associated infections.

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PMID:  Sci Rep. 2022 Sep 1 ;12(1):14890. Epub 2022 Sep 1. PMID: 36050436 Abstract Title:  Antioxidant, cytotoxic, and antibacterial activities of Clitoria ternatea flower extracts and anthocyanin-rich fraction. Abstract:  Clitoria ternatea flower is a traditional medicinal herb that has been used as a natural food colourant. As there are limited studies on investigating the bioactivities of the anthocyanin-rich fraction of Clitoria ternatea flower, this study aimed to determine an efficient column chromatography method to obtain the anthocyanin-rich fraction from this flower and characterise its composition, antioxidant, antibacterial, and cytotoxic activities. Amberlite XAD-16 column chromatography was more efficient in enriching the total anthocyanin content (TAC) of the fraction with the highest TAC to total phenolic content (TPC) ratio of 1:6 than that using C18-OPN. A total of 11 ternatin anthocyanins were characterised in the anthocyanin-rich fraction by LC-MS analysis. The antioxidant activity of the anthocyanin-rich fraction was more potent in the chemical-based assay with an ICvalue of 0.860.07 mg/mL using 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay than cellular antioxidant assay using RAW 264.7 macrophages. In vitro cytotoxicity assay using human embryonic kidney HEK-293 cell line showed the anthocyanin-rich fraction to be more toxic than the crude extracts. The anthocyanin-rich fraction had more potent antibacterial activity than the crude extracts against Bacillus cereus, Bacillus subtilis, and Escherichia coli. The anthocyanin-rich fraction of C. ternatea has the potential to be used and developed as a functional food ingredient or nutraceutical agent.

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POV You crush on Rougee but Karen will crush you maybe. Btw you can also draw Karen in your style if you dare! Use #RangyDTIYS to tag me if you do
#nonpack #nonpackcomic #radrangy #characterdesign
https://www.instagram.com/p/CpY7CmGLfLZ/?igshid=NGJjMDIxMWI=

Bankless co-host David Hoffman retracted his statement that Lido had received a Wells Notice (Danny Nelson/CoinDesk)

Democrats see child migrants as human beings who deserve citizenship rights. Republicans see child migrants as cheap labor to be discarded. 

- skeleton warrior

PMID:  J Biomol Struct Dyn. 2022 Sep 24:1-10. Epub 2022 Sep 24. PMID: 36153001 Abstract Title:  screening of the phytochemicals present inL. as the inhibitors of snake venom phospholipase A(PLA). Abstract:  Millions of people suffer from snake bite envenomation, and its management is a challenge, even today. Medicinal plants have attracted the researcher's attention for their outstanding advantages in treating many diseases, including snake venom poisoning.L, is a plant popularly known for its various pharmacological effects especially, anti-snake venom property. However, the molecular mechanism behind this is poorly understood. It is reported that snake venom PLAis an extensively studied toxic factor. This study is meant to screen the compound's capability to act as inhibitors of thesnake venom PLAthrough molecular docking and dynamics studies. Our results show that among the 27 compounds taken for the study, only Kaempferol showed good interaction profile with the conserved catalytic active site residues, His48 and Asp49. The pharmacophore features of the compound also demonstrate its exact fitting at the binding pocket. Further RMSD, RMSF, Rg, and hydrogen bond analysis confirmed the stable binding of Kaempferol with PLAthrough molecular dynamic simulations for 100ns. In addition, the MM/PBSA binding free energy calculation of the complex was also affirming the docking results. The binding free energy (BFE) of Kaempferolis better than the reference compound. ADME and Lipinski's rule of five reveals its drug like properties.Communicated by Ramaswamy H. Sarma.

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PMID:  Molecules. 2022 Sep 26 ;27(19). Epub 2022 Sep 26. PMID: 36234873 Abstract Title:  Phytochemical Properties and In Vitro Biological Activities of Phenolic Compounds from Flower ofL. Abstract:  Phenolic compounds from the flower ofL. (PCFCTL) were extracted using a high-speed shearing extraction technique and purified by AB-8 macroporous resins, and the phytochemical composition of the purified phenolic compounds from the flower ofL. (PPCFCTL) was then analyzed. Subsequently, its bioactivities including antioxidant properties, enzyme inhibitory activities, and antiproliferative activities against several tumor cell lines were evaluated. Results indicated that the contents of total phenolics, flavonoids, flavonols, flavanols, and phenolic acids in PPCFCTL were increased by 3.29, 4.11, 2.74, 2.43, and 2.96-fold, respectively, compared with those before being purified by AB-8 macroporous resins. The results showed PPCFCTL have significant antioxidant ability (measured by reducing power, RP, and ferric reducing antioxidant power method, FRAP) and good DPPH, ABTS, and superoxide anion radical scavenging activities. They can also significantly inhibit lipase,-amylase, and-glucosidase. In addition, morphological changes of HeLa, HepG2, and NCI-H460 tumor cells demonstrated the superior antitumor performance of PPCFCTL. However, the acetylcholinesterase inhibitory activity was relatively weak. These findings suggest that PPCFCTL have important potential as natural antioxidant, antilipidemic, anti-glycemic and antineoplastic agents in health-promoting foods.

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PMID:  Front Mol Biosci. 2022 ;9:986704. Epub 2022 Sep 30. PMID: 36250019 Abstract Title:  Effects of a plant cyclotide on conformational dynamics and destabilization of-amyloid fibrils through molecular dynamics simulations. Abstract:  Aggregation of-amyloid (A) peptide is one of the hallmarks of Alzheimer's disease (AD) which results in chronic and progressive neurodegeneration of the brain. A recent study by our group have shown the ability of cyclic disulfide-rich peptides ("cyclotides") isolated from a medicinal plant,, to inhibit the aggregation of Apeptides and reduce oxidative stress caused by reactive oxygen species usingmodels of transgenic. In the present study, through extensive computational docking and multi-ns molecular dynamics (MD) simulation, we evaluated if cyclotides can stably bind to Amolecules and/or destabilize the Afibril by preventing conformational changes from-helical to-sheet rich structures. We demonstrate that cyclotides bind effectively and stably to different forms of Astructureshydrogen bonding and hydrophobic interactions. One of the conserved hydrophobic interface residues, Tyr10 was mutated to Ala and the impact of this virtual mutation was estimated by additional MD simulations for the wild-type (WT) and mutant protein-peptide complexes. A detailed MD simulation analyses revealed that cyclotides form hydrogen bonds with the toxic amyloid assemblies thereby weakening the inter-strand hydrogen bonds between the Apeptide. The-distribution map of residues in the cyclotide binding pocket that ideally adopt-sheet conformation show deviation towards right-handed-helical () conformation. This effect was similar to that observed for the Tyr10Ala mutant and doubly so, for the cyclotide bound form. It is therefore possible to hypothesise that the opening up of amyloid-sheet is due to an unfolding process occurring in the Acaused by cyclotide binding and inhibition. Our current findings provide novel structural insights on the mode of interaction between cyclotides and Afibrils and describe their anti-amyloid aggregation potential. This sheds light on the future of cyclotide-based drug design against protein aggregation, a hallmark event in many neurodegenerative diseases.

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PMID:  Pharmaceuticals (Basel). 2022 Nov 13 ;15(11). Epub 2022 Nov 13. PMID: 36422526 Abstract Title:  Asian Pigeonwing Plants () Synergized Mesenchymal Stem Cells by Modulating the Inflammatory Response in Rats with Cisplatin-Induced Acute Kidney Injury. Abstract:  Acute kidney injury is a heterogeneous set of disorders distinguished by a sudden decrease in the glomerular filtration rate, which is evidenced by an increase in the serum creatinine concentration or oliguria and categorized by stage and cause. It is an ever-growing health problem worldwide, with no reliable treatment. In the present study, we evaluated the role ofcombined with mesenchymal stem cells in treating cisplatin-induced acute kidney injury in rats. Animals were challenged with cisplatin, followed by 400 mg/kg of Asian pigeonwing extract and/or mesenchymal stem cells (106 cells/150 g body weight). Kidney functions and enzymes were recorded, and histopathological sectioning was also performed. The expression profile of IL-1, IL-6, and caspase-3 was assessed using the quantitative polymerase chain reaction. The obtained data indicated that mesenchymal stem cells combined with the botanical extract modulated the creatinine uric acid and urea levels. Cisplatin increased the level of malondialdehyde and decreased the levels of both superoxide dismutase and glutathione; however, the dual treatment was capable of restoring the normal levels. Furthermore, all treatments modulated the IL-6, IL-1, and caspase-3 gene expression profiles. The obtained data shed some light on adjuvant therapy usingand mesenchymal stem cells in treating acute kidney injury; however, further investigations are required to understand these agents' synergistic mechanisms fully. The total RNA was extracted from the control, the positive control, and all of the therapeutically treated animals. The expression profiles of the IL-6, IL-1, and caspase-3 genes were evaluated using the real-time polymerase chain reaction. Cisplatin treatment caused a significant upregulation in IL-6. All treatments could mitigate the IL-6-upregulating effect of cisplatin, with the mesenchymal stem cell treatment being the most effective. The same profile was observed in the IL-1and caspase-3 genes, except that the dual treatment (mesenchymal stem cells and the botanical extract) was the most effective in ameliorating the adverse effect of cisplatin; it downregulated caspase-3 expression better than the positive control.

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PMID:  Food Res Int. 2022 Dec ;162(Pt A):112008. Epub 2022 Oct 1. PMID: 36461234 Abstract Title:  Clitoria ternatea blue petal extract protects against obesity, oxidative stress, and inflammation induced by a high-fat, high-fructose diet in C57BL/6 mice. Abstract:  This study examined the chemical compounds and bioactivity of the aqueous extract of Clitoria ternatea blue petals and investigated its beneficial effects in vivo on a mouse model of obesity and metabolic syndrome. The extract mainly contained flavonoids, and nine compounds were tentatively identified. Male C57BL/6J mice were either fed a standard diet (SD) or a high-fat, high-fructose diet (HFFD) for 16 weeks, and HFFD-fed animals were treated with 0.25%, 0.5%, and 2% (w/w) of the aqueous extract in drinking water. The aqueous extract ameliorated oxidative stress and inflammation mediators. Furthermore, the aqueous extract reduced plasma leptin, free fatty acid, low-density lipoprotein cholesterol levels and hepatic malondialdehyde content. The aqueous extract significantly reduced total cholesterol and ameliorated insulin resistance. The results demonstrated that the aqueous extract of C. ternatea blue petals contains bioactive anthocyanins that exert substantial hypolipidemic and anti-inflammatory effects by promoting reverse cholesterol transport in HFFD-fed mice.

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In this interview, repeat guest Tyler LeBaron, MSc., Ph.D., reviews some of the many benefits of molecular hydrogen (H₂). Perhaps most importantly, molecular hydrogen acts as a selective antioxidant, meaning it doesn't indiscriminately suppress free radicals.

It uses your body's own biological systems and feedback loops to identify where and when you're under oxidative stress, and when found, antioxidant genes are stimulated and key antioxidants are transcribed from your DNA. So, molecular hydrogen is not in and of itself a direct radical-scavenging antioxidant. Rather, it helps your body make its own endogenous antioxidants. This is what makes molecular hydrogen so unique.

This is crucial because excessive antioxidants use can be deleterious and molecular hydrogen serves as a redox regulator, so, just like Goldilocks, you get just the right amount, not too much and not too little, which makes your cells very happy.

H₂ Activates Nrf2 Pathway

One of the pathways activated by H₂ when free radicals are present is the Nrf2 pathway. LeBaron explains:

"In your cell you have this protein, Nrf2, and it's attached to Keap1. They're always attached together. But when you get oxidative stress it can cleave off.

[Oxidative stress] causes the cleaving off of the Nrf2 and the Keap1, and the Nrf2 can then diffuse into the nucleus [where] it binds to the ARE, the antioxidant response element of the DNA. [This triggers] the production of all these endogenous antioxidants Phase 2 enzymes of detoxification and antioxidation and there are over 200 of them."

This is one of the primary benefits of molecular hydrogen. It's also what makes molecular hydrogen so useful for such a wide variety of conditions. According to LeBaron, it's been shown to have therapeutic benefits in more than 170 different animal disease models.

"What this means is, for example, there are lots of ways to induce diabetes in an animal model. Using these different models, we can show molecular hydrogen has therapeutic effects. And, yes, the Nrf2 in some cases seems to be extremely important. In fact, by using gene knockout or or interfering RNA, you can blunt the benefits of molecular hydrogen. So, the Nrf2 is very important," LeBaron says.

Molecular Hydrogen Is an Important Nrf2 Regulator

Sulforaphane, found in broccoli, is another well-studied Nrf2 activator. But in contrast to sulforaphane (as well as other Nrf2 activators), molecular hydrogen does not disturb redox homeostasis within the cell by adding too many antioxidants.

R...

In the video above, I'm interviewed by Jason Shurka, author of several books¹ about sacred knowledge, the raising of consciousness and the power we have within.

While my focus has always been to help people take control of their health and achieve optimal well-being by addressing basic lifestyle factors, in recent years, it's become necessary to also enlighten people about the global forces that are trying to seize control, with the ultimate goal of eliminating human rights and freedoms, including your medical freedom.

It's become imperative to understand what these larger forces are trying to achieve, because they're driving The Great Reset agendas, which encompass every aspect of our lives, including food and health care. If you don't understand what their goal is, you will naively go along and become an unwitting victim.

Google Is at the Core of the Global Cabal

As I explain in the interview, Google is a core powerbase of this global cabal, often referred to as the Deep State a hidden power structure based on wealth and financial influence behind (and above) the individual governments of the world because the cabal's control powers hinge on electronic surveillance and social engineering.

Both require massive amounts of data on each individual, and artificial intelligence to predict and control behaviors. Google is the largest controller of data and owns the most advanced AI company in the world. Through their search engine alone, Google controls at least 93% and possibly over 95% of what people are able to see.

They hold the keys to the knowledge of humanity, stored on the internet. And if they don't like what you say, they can bury you to the point where you basically cease to exist. You have no reach, no voice.

I'm no stranger to this censorship process, as I've been under attack ever since I started my website 25 years ago. In 2018, Google finally pulled the plug on me and buried my articles in the deepest recesses of its search engine.

Now, what you find about me are articles that discredit me. You also have to dig deep into the search results to find good information relating to health, nutrition and medicine in general.

There Are Many Levels of Censorship

While more and more people are becoming aware that censorship is happening on social me...

Originally published: April 16, 2020

In March 2020, with the U.S. reeling from the COVID-19 pandemic, the Secure 5G and Beyond Act (S. 893) and the Broadband Deployment Accuracy and Technological Availability Act (S. 1822) were signed into law.

The duo will accelerate the adoption of 5G, or 5th Generation, wireless networks across the U.S. and in so doing, force Americans to receive unprecedented levels of exposure to the millimeter wave (MMW), which has shown potential to harm human health and the environment.

The 5G act requires the president to develop a strategy to ensure the security of 5G mobile telecommunications systems and infrastructures in the U.S., while assisting allies and strategic partners to maximize the security of such systems.¹

The Broadband act requires the Federal Communications Commission (FCC) to issue rules regarding data collection to ultimately improve the accuracy of maps showing where broadband is available in the U.S.²

Whats more, the 5G Act requires the president to consult with the FCC, the Department of Homeland Security, the Department of Defense and other agencies and submit a plan to Congress within 180 days detailing how secure 5G will be implemented.

With millions of Americans suddenly working remotely, its an opportune time for regulators to move 5G forward but its a move that has many experts concerned. Still, the legislation is moving forward under the guise of bringing faster internet to Americans, at any cost. The House Energy and Commerce Committee, which is led by chairman Frank Pallone, Jr., said in a statement:^...

Have you ever gone to buy a new car and gotten tripped up by the what color question? It can be a tough one if youre indecisive, tend to change your mind often, or just arent sure which might be best once youre driving it every single day.

Well, worry no more BMW has a concept car that will allow you to change your cars color with the touch of a button.

The cars are the iX Flow featuring E Ink and the i Vision Dee, and theyre unlike any other car or concept weve seen thus far.

PMID:  Nutrients. 2021 Sep 16 ;13(9). Epub 2021 Sep 16. PMID: 34579104 Abstract Title:  Possible Role of Butyrylcholinesterase in Fat Loss and Decreases in Inflammatory Levels in Patients with Multiple Sclerosis after Treatment with Epigallocatechin Gallate and Coconut Oil: A Pilot Study. Abstract:  (1) Background. Multiple sclerosis (MS) is characterised by the loss of muscle throughout the course of the disease, which in many cases is accompanied by obesity and related to inflammation. Nonetheless, consuming epigallocatechin gallate (EGCG) and ketone bodies (especially-hydroxybutyrate (HB)) produced after metabolising coconut oil, have exhibited anti-inflammatory effects and a decrease in body fat. In addition, butyrylcholinesterase (BuChE), seems to be related to the pathogenesis of the disease associated with inflammation, and serum concentrations have been related to lipid metabolism. Objective. The aim of the study was to determine the role of BuChE in the changes caused after treatment with EGCG and ketone bodies on the levels of body fat and inflammation state in MS patients. (2) Methods. A pilot study was conducted for 4 months with 51 MS patients who were randomly divided into an intervention group and a control group. The intervention group received 800 mg of EGCG and 60 mL of coconut oil, and the control group was prescribed a placebo. Fat percentage and concentrations of the butyrylcholinesterase enzyme (BuChE), paraoxonase 1 (PON1) activity, triglycerides, interleukin 6 (IL-6), albumin andHB in serum were measured. (3) Results. The intervention group exhibited significant decreases in IL-6 and fat percentage and significant increases in BuChE,HB, PON1, albumin and functional capacity (determined by the Expanded Disability Status Scale (EDSS)). On the other hand, the control group only exhibited a decrease in IL-6. After the intervention, BuChE was positively correlated with the activity of PON1, fat percentage and triglycerides in the intervention group, whereas these correlations were not observed in the control group (4). Conclusions. BuChE seems to have an important role in lipolytic activity and the inflammation state in MS patients, evidenced after administering EGCG and coconut oil as aHB source.

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Dane Wigington GeoengineeringWatch.org The manufactured snowpocalypse is wreaking havoc on countless communities and crop producing regions, welcome to winter weather warfare. Many of the locations that are now buried under snow saw temperatures of 80 degrees or more in the days just prior to the commencement of the climate engineering winter weather warfare operations. Matrix media propagandists

Could your kitchen counter space use some additional room to house all your coffee essentials? Heres how to double up space with this easy and cool IKEA crate coffee station! Last summer, I had picked up some small Ikea crates to make a few herb-themed planters. Have you ever picked up an IKEA crate before? []

The post Rustic Ikea crate coffee station appeared first on Funky Junk Interiors.

PMID:  Food Funct. 2023 Jan 23 ;14(2):1062-1071. Epub 2023 Jan 23. PMID: 36594273 Abstract Title:  Improvements in gait and balance in patients with multiple sclerosis after treatment with coconut oil and epigallocatechin gallate. A pilot study. Abstract:  Multiple sclerosis (MS) is a neurodegenerative disease that progressively decreases the muscular and functional capacity. Thus, there is an alteration in the ability to walk that affects balance, speed and resistance. Since MS pathology involves neuroinflammation, cellular oxidation and mitochondrial alterations, the objective of the study was to assess the impact of a nutritional intervention with coconut oil and epigallocatechin gallate (EGCG) on gait and balance. In order to do this, 51 patients with MS were enrolled and randomly distributed into an intervention group and a control group, which received either a daily dose of 800 mg of EGCG and 60 ml of coconut oil, or a placebo, all during a period of 4 months and which followed a Mediterranean isocaloric diet. Initial and final assessments consisted of the evaluation of quantitative balance (Berg scale), perceived balance (ABC scale), gait speed (10MWT) and resistance (2MWT). Besides, muscle strength was measured using a dynamometer and levels of-hydroxybutyrate (BHB) were measured in serum samples. In the intervention group, there was a significant improvement in the gait speed, quantitative balance and muscle strength of the right quadriceps; an improvement in gait resistance was observed in both groups. There were also significant and positive correlations between balance and gait scales. In conclusion, the administration of EGCG and coconut oil seems to improve gait speed and balance in MS patients, although the latter was not perceived by them. Furthermore, these variables appear to be related and contribute to functionality.

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I have a confession...

I'm a sucker for "Before and After" pics, but I like to take before and after pictures of my gardens.
It keeps me motivated when I'm weeding or trying to be patient while my seedlings and fruit trees to grow.

This is a Bosworth (Kwai Mai Pink) Lychee tree that I planted a few springs ago. The "Before pic" is from April of 2021 (a year after I planted it) and the "After" pic is from April of 2022. I will take another updated picture this upcoming spring.

Lychee was...

Do you take before and after pictures with your garden?

By Cathy Jameson

A few times now when I'm scheduled to leave the house later than usual, something has happened with Ronan - a fever, a possible seizure (they can happen so fast), or a wonky episode of something worrisome (I don't know yet what to call it).  It happened again one day last week.  Ronan looked confused, held his head, closed his eyes and looked wobbly on his feet.  I was worried, since it whatever it was, came out of the blue. 

While getting him off his feet and to the couch, I sat next to him, ready to administer emergency seizure medication, should it be a seizure.  I was ready to clean up throw up, should it have been an upset tummy rumbling.  But Ronan, who could only grip my arms as I reached out to hold him, laid on the couch and drifted off to sleep.  He ended up taking two naps, even though hed had a great night of sleep. 

The day that happened, I wasnt scheduled to leave the house until 1:00. 

The time before, he was also wobbly on his feet and knew something was different but couldnt express anything but a worried look on his face.  Ronan had woken up that day and was fine but then wasnt.  That day was the first day that my work hours had changed, and I happened to be home.  Both times, I didn't know it, whatever it is, was going to happen, but God knew I needed to be with my bud.  I got to hold his hand, to calm his nerves, to settle him quickly, to watch him quietly fall back asleep to witnessing him wake up refreshed as if nothing worrisome or wonky had just happened.

Ive spent the last few days trying to figure out what triggered the odd episodes.  We havent changed brands of foods he and I have for breakfast.  The supplements taken are the same as always.  Other products found in a home laundry soap, dish soap, bath soap and more, are all the same.  Granted, we had the huge medication fiasco a few weeks ago, but this happened while on generics and since hes been back on his regular doses and brands.  I joked with a friend when I knew Id be home all morning again, I hope nothing happens to Ronan while Im home past lunchtime!  All joking aside, its just so odd and definitely something I definitely need to track. 

I was thankful I was home both times.  I truly felt like I was at the right place at the right time. 

Another time, I was thankful for somethin...

PMID:  Surg Neurol Int. 2021 ;12:141. Epub 2021 Apr 8. PMID: 33948312 Abstract Title:  Spontaneous regression of herniated cervical disc: A case report and literature review. Abstract:  BACKGROUND: We have reviewed 75 cases plus our own single instance of spontaneous regression of herniated cervical discs.METHODS: We searched PubMed and EMBASE databases (until September 2020) utilizing the following keywords; "spontaneous regression," "herniated cervical disc," and "Magnetic Resonance Imaging (MRI) studies."RESULTS: In the literature, we found 75 cases of herniated cervical discs which spontaneously regressed; to this, we added our case. Patients averaged 40.95 years of age. Discs were paracentral or foraminal in 84% of the cases, with most occurring at the C5-C6 (51%) and C6-C7 (36%) levels. Symptoms included neck pain/radiculopathy (91%) or myelopathy (9%). The average interval between initial presentation and spontaneous regression of herniated discs on MRI was 9.15 months. Interestingly, on MRI, extruded/sequestrated discs were more likely to undergo spontaneous regression versus protruding discs.CONCLUSION: Successive MRI studies documented the spontaneous regression of herniated cervical discs over an average of 9.15 months. Although this may prompt greater consideration for conservative treatment in younger patients without neurologic deficits, those with deficits should be considered for surgery.

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PMID:  World Neurosurg. 2019 Jan 3. Epub 2019 Jan 3. PMID: 30610984 Abstract Title:  Spontaneous Resorption of Herniated Lumbar Disk: Observational Retrospective Study in 9 Patients. Abstract:  BACKGROUND: Spontaneous resorption of herniated lumbar disk was explained in the literature by different mechanisms, and multiple predictive factors for resorption were reported in numerous studies. The purpose of this study was to evaluate the phenomena of spontaneous resorption of herniated lumbar disk without surgery (mechanisms, predictive factors, expected time for resorption, and proper time for conservative treatment).METHODS: This retrospective clinical case series included 9 patients with herniated lumbar disk on initial magnetic resonance imaging (MRI). The mean age was 396.3 years, and the male to female ratio was 2:1. All patients presented with back pain and sciatica without motor deficit. All patients refused surgical intervention; therefore, they were treated conservatively. Patients were followed-up clinically and radiologically (MRI) in the outpatient clinic on regular visits (for 18 months).RESULTS: Spontaneous resorption of herniated disk was found in all patients in a mean time of 8.73.2 months. All patients recovered clinically in a mean time of 5.71.6 weeks by conservative treatment. Large and/or sequestrated disks were associated with rapid resorption. Early recovery patients showed early spontaneous resorption of the disk.CONCLUSIONS: Spontaneous resorption of herniated lumbar disk can occur by different mechanisms (retraction, dehydration, and inflammatory mediated mechanism). Large and/or sequestrated disks are essential predictive factors for rapid spontaneous resorption. Furthermore, early clinical recovery is usually associated with quick resorption of the herniated disk.

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Any one dip their toe in the world of bulk military powder?
What's not to love? It's cheap, real cheap, lot to lot consistency sucks, chances are you will be developing loads for each lot but it's so cheap just buy a lifetime supply, or enough to load several tens of thousands of rounds. Some of them are weird, just takes some experimenting to find loads.
When I say cheap it's around half the price of domestically made commercial powder.
The one I have now is called CBI made by general...

Bulk military powder

Delay in Silvergates financials sparks fears over bankruptcy, FTX reports $8.6B deficit and Binances balance sheet sought by U.S. senators.

PMID:  Appl Physiol Nutr Metab. 2015 Sep ;40(9):899-906. Epub 2015 May 4. PMID: 26288392 Abstract Title:  Potential ergogenic activity of grape juice in runners. Abstract:  Recent studies have indicated that certain food products have ergogenic potential similar to that of sports supplements. The present study aimed to investigate the potential ergogenic effect of integral purple grape juice on the performance of recreational runners. Twenty-eight volunteers of both sexes (age, 39.88.5 years; peak oxygen consumption, 43.28.5 mL/(kgmin)) were randomized into either a group that received grape juice (grape juice group (GJG), n = 15; 10 mL/(kgmin) for 28 days) or a group that received an isocaloric, isoglycemic, and isovolumetric control beverage (control group (CG), n = 13). A time-to-exhaustion exercise test, anaerobic threshold test, and aerobic capacity test were performed, together with assessments of markers of oxidative stress, inflammation, immune response, and muscle injury, performed at baseline and 48 h after the supplementation protocol. The GJG showed a significant increase (15.3%) in running time-to-exhaustion (p = 0.002) without significant improvements in either anaerobic threshold (3.6%; p = 0.511) or aerobic capacity (2.2%; p = 0.605). In addition, GJG exhibited significant increases in total antioxidant capacity (38.7%; p = 0.009), vitamin A (11.8%; p = 0.016), and uric acid (28.2%; p = 0.005), whereas-1-acid glycoprotein significantly decreased (20.2%; p = 0.006) and high-sensitivity C-reactive protein levels remained unchanged. In contrast, no significant changes occurred in any of these variables in the CG. In conclusion, supplementation with purple grape juice shows an ergogenic effect in recreational runners by promoting increased time-to-exhaustion, accompanied by increased antioxidant activity and a possible reduction in inflammatory markers.

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How divided is the country. Division by ethics, belief, philosophy, values, politics, social issues, etc. and how can we once again become a United States of America instead of the Divided?

PMID:  Eur J Nutr. 2020 Oct ;59(7):2997-3007. Epub 2019 Nov 15. PMID: 31732851 Abstract Title:  A single dose of purple grape juice improves physical performance and antioxidant activity in runners: a randomized, crossover, double-blind, placebo study. Abstract:  PURPOSE: To investigate the effects of a single dose of juice on physical performance, oxidative stress, inflammation and muscle damage in runners.METHODS: Fourteen recreational male runners (399 years, VO=55.96.5 ml/kg/min) performed two running tests to exhaustion at 80% of VOafter ingesting grape juice or a placebo drink (10 ml/kg/day) randomly. Blood samples were taken before and 2 h after supplementation and immediately after running to analyze total antioxidant capacity (TAC), malondialdehyde (MDA), alpha-1 acid glycoprotein (A1GPA), high-sensitivity C-reactive protein (hs-CRP), creatine kinase (CK) and lactate dehydrogenase (LDH).RESULTS: The participants ran for an average of 59.227.8 min until exhaustion in the placebo group and for 68.429.7 min until exhaustion in the grape juice intake group, which was a significantly longer time (p=0.008). This improvement in physical performance was accompanied by a 43.6% increase in TAC (p=0.000) at the post-exercise timepoint compared to the level at baseline. MDA, A1GPA, hs-CRP, CK, and LDH did not exhibit changes. In contrast, no significant change in any variable was observed after consuming the placebo drink.CONCLUSION: The single-dose intake of purple grape juice demonstrated an ergogenic effect in recreational runners by increasing run time to exhaustion and increasing antioxidant activity.

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PMID:  Complement Ther Med. 2020 Nov ;54:102570. Epub 2020 Sep 15. PMID: 33183673 Abstract Title:  Effects of grape juice consumption on oxidative stress and inflammation in male volleyball players: A randomized, double-blind, placebo-controlled clinical trial. Abstract:  INTRODUCTION: Some foods are also demonstrated benefits, such as anti-inflammatory, antioxidant, and ergogenic activity, similar to that of sports supplements. Grape juice has been considered an important source of polyphenols and these compounds could promote positive effects to the sports players. In this sense, the objective was to evaluate the effects of purple grape juice consumption on indicators of oxidative stress, inflammation, muscle damage, global histone H4 acetylation levels, and muscle strength and muscle power in volleyball athletes.METHODS: This is a randomized double-blind clinical trial in which 12 male volleyball players (160.6 years old) participated in three different moments with match simulation: control (without beverage) (WB), grape juice (GJ) and placebo (PLA) (400 mL/day of grape juice or placebo (maltodextrin) for 14 days in a cross-over model). Before and immediately after each match, blood collection for analysis of indicators of systemic redox status, systemic concentrations of Interferon-(IFN-) and Interleukin-4 (IL-4), muscle damage, by Creatine Kinase (CK-NAC) and levels of global histone H4 acetylation were performed, as well as handgrip strength (HG) and lower limb power tests.RESULTS: Consumption of grape juice significantly reduced lipid peroxidation (p = 0.04) and Deoxyribonucleic Acid (DNA) damage (p = 0.01) after the match. IFN-levels, IL-4, CK-NAC, and histone H4 acetylation post-match did not alter with the grape juice consumption. Lower limb power improved after acute exercise in WB and GJ conditions (p

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This is actually just for fun but hey all how about posting your opinion and your fav?


Why The 1911 Is Better Than Glock


Everyone who watchs The Firearm Blog on YouTube should know Patrick is a massive Glock fanboy. Awhile back Patrick got a job at Brownells and refused to ship...

Let the WAR begin! (MUHAHAHAHAHAHAAAAaaaaa) glock vs 1911

PMID:  An Acad Bras Cienc. 2020 ;92(4):e20191551. Epub 2020 Nov 20. PMID: 33237140 Abstract Title:  Effects of grape juice consumption on muscle fatigue and oxidative stress in judo athletes: a randomized clinical trial. Abstract:  Physiological levels of reactive oxygen species (ROS) are important for intracellular and extracellular redox regulation in signaling and defense processes. Strenuous exercise can also contribute to this imbalance, and the muscle fatigue, evidenced by impaired strength or power generation, can be caused by various reasons, including oxidative stress. Antioxidants can prevent the formation of ROS by intercepting free radicals. Twenty judo athletes were included in this randomized, double-blind clinical trial into grape juice and placebo groups, and they consumed grape juice or placebo daily for 14 days in a crossover model. The outcomes were analyzed before and after combat simulations. The upper limb strength was higher in the grape juice group than in the placebo (p [group] = 0.003). The lipid damage levels were 10% higher in the placebo group (p [interaction] = 0.048). During the pre-exercise, the placebo group showed 19% more DNA damage than the grape juice group. The superoxide dismutase activity was 80% lower in the grape juice group (p [interaction]

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Multicoin's Kyle Samani (Danny Nelson/CoinDesk)

There are some things were really used to seeing from one angle only, such as the Mona Lisa and the podium in the Whte House press room.

On Reddits r/AlternateAngles forum, theres a wealth of images showing familiar things in a way we dont usually see them.

Check out these great examples.

1. A world of difference

(Via)

2. Giza look at the pyramid, mate.

(Via)

3. Get back

(Via)

4. A long time ago in a film studio far, far away

(Via)

5. Say cheese

(Via)

6. Get an eyeful of the Towers bottom

(Via)

7. The Price is Wrong

...

PMID:  Breast Cancer Res Treat. 2014 Jun ;145(2):371-9. Epub 2014 Apr 10. PMID: 24718774 Abstract Title:  Ultra-low-dose estriol and Lactobacillus acidophilus vaginal tablets (Gynoflor()) for vaginal atrophy in postmenopausal breast cancer patients on aromatase inhibitors: pharmacokinetic, safety, and efficacy phase I clinical study. Abstract:  Phase I pharmacokinetic (PK) study assessed circulating estrogens in breast cancer (BC) patients on a non-steroidal aromatase inhibitor (NSAI) with vaginal atrophy using vaginal ultra-low-dose 0.03 mg estriol (E3) and Lactobacillus combination vaginal tablets (Gynoflor()). 16 women on NSAI with severe vaginal atrophy applied a daily vaginal tablet of Gynoflor() for 28 days followed by a maintenance therapy of 3 tablets weekly for 8 weeks. Primary outcomes were serum concentrations and PK of E3, estradiol (E2), and estrone (E1) using highly sensitive gas chromatography-mass spectrometry. Secondary outcomes were clinical measures for efficacy and side effects; microscopic changes in vaginal epithelium and microflora; and changes in serum FSH, LH, and sex hormone-binding globulin. Compared with baseline, serum E1 and E2 did not increase in any of the women at any time following vaginal application. Serum E3 transiently increased after the first application in 15 of 16 women, with a maximum of 168 pg/ml 2-3 h post-insertion. After 4 weeks, serum E3 was slightly increased in 8 women with a maximum of 44 pg/ml. The vaginal atrophy resolved or improved in all women. The product was well tolerated, and discontinuation of therapy was not observed. The low-dose 0.03 mg E3 and Lactobacillus acidophilus vaginal tablets application in postmenopausal BC patients during AI treatment suffering from vaginal atrophy lead to small and transient increases in serum E3, but not E1 or E2, and therefore can be considered as safe and efficacious for treatment of atrophic vaginitis in BC patients taking NSAIs.

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https://banned.video/watch?id=63ff828485d91c3d2e72e5cd
FIGHT BACK! - Safety Committees of the Revolution
Prior to 1776, American patriots lawfully nullified British rule by creating their own parallel government The Reese Report | Greg Reese | Substack

PMID:  Int J Clin Pharmacol Ther. 2022 Sep ;60(9):384-391. PMID: 35713160 Abstract Title:  Effect of vitamin C on immune reconstitution after bone marrow transplantation. Abstract:  BACKGROUND: Vitamin C is an essential nutrient for the adequate function and maturation of the immune system. In vitro studies show that the development, proliferation, and functioning of T cells requires vitamin C, especially for natural killer (NK) cells. Their deficiency during the acute phase post-transplantation could cause greater morbidity and mortality in these patients. A prospective clinical trial using high-dose vitamin C was performed to determine if vitamin C supplementation improves reconstitution of NK lymphocytes after hematopoietic stem cell transplantation (HSCT).MATERIALS AND METHODS: We enrolled 24 patients who underwent autologous HSCT for multiple myeloma and lymphoma. Patients were randomized to receive standard treatment or standard treatment plus 20 g vitamin C once daily (1 - 10 days) and 500 mg twice daily (11 - 100 days) after transplantation.RESULTS: NK and CD3lymphocytes showed an increase from days +30 to +100 only in the vitamin C-treated group. Patients in the vitamin C group had a lower frequency of infections. No severe adverse events were reported.CONCLUSION: Our results suggest that high-dose vitamin C supplementation is an effective and safe therapeutic option to decrease the frequency of infections and enhance immune reconstitution after HSCT.

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Dubai-based Bybit is the latest crypto exchange to suspend U.S. dollar wire transfers, claiming partner disruptions.

Here we go again. After a very successful hip replacement in March of this year I had a total knee replacement (knee arthroplasty) today. I also got a new knee cap, whatever that's called.

This knee had been going down hill slowly since I had the leg crushed in 1982. I haven't been able to straighten the knee since then, and the doctor measured the angle at 19 degrees. The new knee has only a 1 degree bend. The muscles and tendons are all accustomed to the old bend and they'll need...

Hot Diggity's knee replacement thread

PMID:  JAMA Netw Open. 2022 Oct 3 ;5(10):e2239380. Epub 2022 Oct 3. PMID: 36315143 Abstract Title:  Effect of High-Intensity Interval Training in Patients With Atrial Fibrillation: A Randomized Clinical Trial. Abstract:  IMPORTANCE: Patients with atrial fibrillation (AF) experience poor functional capacity and quality of life (QOL). High-intensity interval training (HIIT) has been shown to elicit greater improvements in functional capacity and QOL compared with moderate to vigorous intensity continuous training (MICT) in other cardiovascular populations, yet HIIT remains understudied in AF.OBJECTIVE: To compare the effects of 12 weeks of HIIT and MICT-based cardiovascular rehabilitation (CR) on functional capacity and general QOL in patients with persistent and permanent AF. Disease-specific QOL, resting heart rate (HR), time in AF, and physical activity (PA) levels were also assessed.DESIGN, SETTING, AND PARTICIPANTS: This randomized clinical trial, conducted between November 17, 2015, and February 4, 2020, at a tertiary-care cardiovascular health center in Ottawa, Canada, recruited 94 patients with persistent and permanent AF.INTERVENTIONS: High-intensity interval training (23 minutes: two 8-minute interval training blocks of 30-second work periods at 80%-100% of peak power output interspersed with 30-second recovery) or CR (60 minutes: continuous aerobic conditioning within 67%-95% of peak HR and 12-16 of 20 ratings of perceived exertion) twice weekly for 12 weeks.MAIN OUTCOMES AND MEASURES: The primary outcomes were changes in functional capacity (6-minute walk test [6MWT] distance) and general QOL (Short Form 36) from baseline to 12 weeks' follow-up. Secondary outcomes included changes in disease-specific QOL (Atrial Fibrillation Severity Scale), resting HR, time in AF, and PA levels. An intention-to-treat analysis was used to compare changes between groups.RESULTS: Of the 94 patients who consented, 86 participated (mean [SD] age, 69 [7] years; 57 [66.3%] men). No significant differences in improvements in 6MWT distance (mean [SD], 21.3 [34.1] vs 13.2 [55.2] m; P=.42) and general QOL (Physical Component Summary, 0.5[6.1] vs 1.1 [4.9] points; P=.87) between HIIT and CR were observed. No significant differences in improvements in disease-specific QOL (AF symptoms: -1.7 [4.3] vs -1.5 [4] points, P=.59), resting HR (-3.6 [10.6] vs -2.9 [12.4] beats per minute, P=.63), and moderate to vigorous PA levels (37.3 [93.4] vs 14.4 [125.7] min/wk; P=.35) between HIIT and CR were detected. Participants attended a mean (SD) of 18.3 (6.1) (75.1%) HIIT sessions and 20.0 (4.5) (83.4%) CR sessions (P=.36).CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, twice-weekly 23-minute HIIT was as efficacious as twice-weekly 60-minute CR in improving functional capacity, general...

You may have made it through another week, but have you made it through the most important news stories from the last seven days? If not, youre in luck.

HOA Orders Danzig to Take Down Halloween Decorations

Read the full story here.

What the Fuck: This Guy Is Listening to the Mountain Goats While Lifting

Read the full story here.

Read the full story here.

...

Hair dryers work great to thaw out a frozen car in the morning. Hang it from rear view mirror or ? Crank it on high and go do your thing for a bit. Off you'll go. (Caution. Females get angry if they can't find theirs. Always return it)

Post a picture of your choice.

Rules:
One a day
Must be taken by you.
Any subject matter you want.
I'll start
my Favorite fishing spot.

PMID:  Scand J Med Sci Sports. 2022 Nov 25. Epub 2022 Nov 25. PMID: 36427275 Abstract Title:  High-intensity interval training improves metabolic syndrome in women with breast cancer receiving Anthracyclines. Abstract:  INTRODUCTION: Anthracycline chemotherapy is a frequent treatment for breast cancer, whereas it can increase risk of physiologic side-effects, such as metabolic syndrome (MetS). Exercise has been used as a non-pharmacological strategy to decrease MetS. Specifically, high-intensity interval training (HIIT) has been shown to improve MetS in patients with diabetes or cardiac rehabilitation patients; however, the effects of HIIT on MetS and associated biomarkers in patients with breast cancer receiving anthracycline chemotherapy have not been previously explored. Therefore, we purposed to determine the effects of HIIT on MetS in breast cancer patients undergoing anthracycline chemotherapy.METHODS: In total, 30 patients with breast cancer were recruited prior to initiating treatment and randomized into HIIT (n = 15) or control (n = 15). The HIIT group attended supervised cycling sessions 3days/week for 8weeks. MetS was assessed by waist circumference, blood pressure, fasting levels of high-density lipoprotein cholesterol (HDL-C), triglycerides, and glucose. Circulating levels of MetS-related biomarkers were also measured (total cholesterol, insulin, HbA1c, leptin, adiponectin, and c-reactive protein).RESULTS: After 8weeks, MetS z-score was significantly improved in the HIIT group compared with controls (-7.60, 95% CI: -9.08 to -6.13, p

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PMID:  Exp Gerontol. 2023 Jan ;171:112039. Epub 2022 Nov 25. PMID: 36442700 Abstract Title:  The effect of high intensity interval training with genistein supplementation on mitochondrial function in the heart tissue of elderly rats. Abstract:  INTRODUCTION: For the most part, heart disease increases with age; on the other hand, although the role of exercise and antioxidants in the health of the elderly has been reported, the simultaneous effect of these two interventions is a new research topic. Thus, the aim of this study was to evaluate the effect of eight weeks of high intensity interval training (HIIT) and genistein (G) supplementation on oxidative stress, apoptosis and mitochondrial biogenesis in the heart tissue of elderly rats.METHODS: In this experimental study, 40 elderly female Sprague-Dawley rats aged 20  2 months and weighing 250  30 g were randomly divided into five groups of eight animals, including: (1) control (C), (2) sham (Sh), (3) HIIT, (4) HIIT + G and (5) G. Also, to evaluate the effect of time passage on the variables, 8 healthy young rats were included in the healthy young control group. HIIT protocol was performed for eight weeks, three sessions with an intensity of 95-90 % VOat high intensity intervals and 45-45 % VOat low intensity intervals. Ge was received daily at a dose of 60 mg/kg peritoneally. Data analysis was performed using one-way ANOVA with Tukey's post hoc test (P  0.05).RESULTS: In the HIIT and HIIT + G groups, levels of Bax, Bax/Bcl-2 ratio, MDA, PAB, GSSG were lower and levels of PGC-1, TFAM, GSH, GSH/GSSG ratio and NDUFS7 were higher than the control and sham groups (P  0.05). In the HIIT + G group, levels of Bcl-2 were significantly higher than the control group (P  0.05). In the HIIT + G group, levels of Bax, GSSG, Bax/Bcl-2 ratio, and PAB were lower, and levels of GSH/GSSG ratio, Bcl-2, PGC-1, TFAM and NDUFS7 were higher than the G consumption group (P  0.05). In the HIIT + G group, levels of PGC-1and TFAM were significantly higher and levels of MDA and PAB were lower than the HIIT group (P  0.05).CONCLUSION: Both HIIT and G consumption seem to have beneficial effects on reducing oxidative stress; in addition, the interaction of these two variables on the improvement of apoptosis and mitochondrial biogenesis is more favorable than the effect of either one alone. However, more studies are needed on different pathways of apoptosis following G administration.

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PMID:  Front Cardiovasc Med. 2022 ;9:1046560. Epub 2022 Nov 17. PMID: 36465439 Abstract Title:  The impact of high-intensity interval training on vascular function in adults: A systematic review and meta-analysis. Abstract:  AIM: We performed a systematic review and meta-analysis to investigate the effects of high-intensity interval training (HIIT) compared with moderate-intensity continuous training (MICT) or with no exercise (CON) on vascular function in adults who were free of cardiometabolic diseases and those with cardiometabolic diseases.METHODS: A search across three electronic databases including Scopus, PubMed, and Web of Science was conducted through February 2022 to identify the randomized trials evaluating HIIT vs. MICT and/or CON on vascular function as measured using brachial artery flow-mediated dilation (FMD) in adults. Separate analyses were conducted for HIIT vs. MICT and/or CON to calculate weighted mean differences (WMD) and 95% confidence intervals (95% CIs) using random or fixed models.RESULTS: A total of 36 studies involving 1,437 participants who were either free of cardiometabolic diseases or had cardiometabolic diseases were included in the meta-analysis. HIIT effectively increased FMD when compared with MICT [1.59% (95% CI 0.87-2.31),= 0.001] or CON [3.80% (95% CI 2.58-5.01),= 0.001]. Subgroup analysis showed that HIIT increased FMD in participants with cardiovascular and metabolic diseases, but not in participants who were free of cardiometabolic diseases. In addition, HIIT effectively increased FMD regardless of age and body mass index.CONCLUSION: We confirm that HIIT is effective for improving vascular function in individuals with metabolic disorders and cardiovascular diseases and has a superior effect compared to MICT, demonstrating time efficiency.SYSTEMATIC REVIEW REGISTRATION: [https://www.crd.york.ac.uk/prospero], identifier [CRD42022320863].

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PMID:  Curr Alzheimer Res. 2022 Dec 7. Epub 2022 Dec 7. PMID: 36503461 Abstract Title:  High-Intense Interval Training Prevents Cognitive Impairment And Increases The Expression Of Muscle Genes Fndc5 And Ppargc1a In A Rat Model Of Alzheimer's Disease. Abstract:  BACKGROUND: Alzheimer's disease is the most common neurodegenerative disease in the world, characterized by the progressive loss of neuronal structure and function, whose main histopathological landmark is the accumulation of-amyloid in the brain.OBJECTIVE: It is well known that exercise is a neuroprotective factor and that muscles produce and release myokines that exert endocrine effects in inflammation and metabolic dysfunction. Thus, this work intends to establish the relationship between the benefits of exercise through the chronic training of HIIT on cognitive damage induced by the Alzheimer's model by the injection ofamyloid 1-42.METHODS: For this purpose, forty-eight male Wistar rats were divided into four groups: Sedentary Sham (SS), Trained Sham (ST), Sedentary Alzheimer's (AS), and Trained Alzheimer's (AT). Animals were submitted to stereotactic surgery and received a hippocampal injection of A1-42 or a saline solution. Seven days after surgery, twelve days of treadmill adaptation followed by five maximal running tests (MRT) and fifty-five days of HIIT, rats underwent the Morris water maze test. The animals were then euthanized, and their gastrocnemius muscle tissue was extracted to analyze the Fibronectin type III domain containing 5 (FNDC5), PPARG Coactivator 1 Alpha (PPARGC1A), and Integrin subunit beta 5 (ITGB5-R) expression by qRT-PCR in addition to cross-sectional areas.RESULTS: The HIIT prevents the cognitive deficit induced by the infusion of amyloid1-42 (p

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The proposal restricts Sam Bankman-Frieds communication to a flip phone or another non-smartphone device without internet access.

PMID:  J Strength Cond Res. 2023 Mar 1 ;37(3):688-709. Epub 2022 Nov 15. PMID: 36508686 Abstract Title:  Effects of Concurrent Resistance and Endurance Training Using Continuous or Intermittent Protocols on Muscle Hypertrophy: Systematic Review With Meta-Analysis. Abstract:  Monserd-Vilar, A, Balsalobre-Fernndez, C, Hoffman, JR, Alix-Fages, C, and Jimnez, SL. Effects of concurrent resistance and endurance training using continuous or intermittent protocols on muscle hypertrophy: Systematic review with meta-analysis. J Strength Cond Res 37(3): 688-709, 2023-The purpose of this systematic review with meta-analysis was to explore the effects of concurrent resistance and endurance training (CT) incorporating continuous or intermittent endurance training (ET) on whole-muscle and type I and II muscle fiber hypertrophy compared with resistance training (RT) alone. Randomized and nonrandomized studies reporting changes in cross-sectional area at muscle fiber and whole-muscle levels after RT compared with CT were included. Searches for such studies were performed in Web of Science, PubMed, Scopus, SPORTDiscus, and CINAHL electronic databases. The data reported in the included studies were pooled in a random-effects meta-analysis of standardized mean differences (SMDs). Twenty-five studies were included. At the whole-muscle level, there were no significant differences for any comparison (SMD0.33) or combined with continuous ET (SMD>0.27), but not compared with CT incorporating only continuous ET (SMD

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A shimmering reminder that the magic is of our own conjuring.

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There are seasons of being when a cloak of meaninglessness seems to slip over you, over everything, muffling the song of life. It is not depression exactly, though the two conditions make eager bedfellows. Rather, it is a great hollowing that empties you of that vital force necessary for moving through the world wonder-smitten by reality, that glint of gladness at the mundane miracle of existence. A disenchantment we may call by many names burnout, apathy, alienation but one that visits upon every life in one form or another, at one time or another, pulsating with the unmet longing for something elemental and ancient, with the yearning to see the world as beautiful again and feel its magic, to find sanctuary in it, to contact that submerged sunrise of wonder.

Katherine May explores what it takes to shed the cloak of meaninglessness and recover the sparkle of vitality in Enchantment: Awakening Wonder in an Anxious Age (public library) a shimmering chronicle of her own quest for a better way t...

This article was originally published by Michael Snyder at The Economic Collapse Blog. 

By the end of this month, there will be no more Walmart stores in Portland.  More than 641,000 people live within the city limits of Portland, so you would think that there should be a lot of money to be made there.

But Walmart has decided to wave the white flag.  Portland has been transformed into a complete and utter hellhole, and apparently, Walmart executives have determined that things are not going to turn around any time soon.  So they have announced that the last two Walmart stores in Portland that were still operational will be permanently shut down by the end of March

The last two Walmart stores within Portlands city limits will close in late March, the company announced.

The locations, at 1123 North Hayden Meadows Drive and at 4200 Southeast 82nd Avenue at the Eastport Plaza, will both close on Friday, March 24. Walmart says they are closing the stores because they were not meeting financial expectations.

A spokesperson for Walmart used very careful language to explain why these stores are being closed

The decision to close these stores was made after a careful review of their overall performance. We consider many factors, including current and projected financial performance, location, population, customer needs, and the proximity of other nearby stores when making these difficult decisions. After we decide to move forward, our focus is on our associates and their transition, which is the case here, a spokesperson with Walmart said.

Of course, this isnt exactly the truth.

But what do you expect Walmart to say?

Do you expect a corporate spokesperson to admit that Walmart is leaving Portland because it has become a drug-ridden, crime-infested hellhole?

One customer that was interviewed about the store closings addressed the real reason why Walmart is leaving

We gotta resolve the shoplifting one way or another, she added, addressing the topic of retail theft at the citys locations, because that is simply the problem. Its gotta stop.

At this point, much of Portland has been turned into a giant tent city for the homeless.

.....

Theres no one right way to be married, or to stay married, but I think most people who are doing it would tell you that being able to laugh at yourself or the situation is up there as far as hacks.

And if thats true, these 26 people are going to stay married for a long, long time.

26. Im on the wifes side here.

Sorry not sorry.

I'm your wife. You might remember me from such hits as "We are leaving in two minutes" and its sequel "Why are you in the shower?"

Sarcastic Mommy (@sarcasticmommy4) November 10, 2022

25. Hes giving you permission.

Youve gotta jump on that.

I love when my husband says, correct me if Im wrong, like I would pass up that opportunity.

MumOfTwo (@MumOfTw0) November 15, 2022

24. Finally.

Hes been trying to get fired for a long time.

So i just learned after 27 years of ummsure i guess so, yeah but the other one looked nice too i have been fired as my wifes fashion consultant and my daughter now has that job

Diedrich Bader (@bader_diedrich)...

By Tyler Durden The aftermath of the freight train derailment in East Palestine, Ohio, persists, with residents and rail workers reporting illnesses and the Biden administration facing criticism regarding an inadequate federal response. The 38-car derailment occurred one month ago and resulted in the release of vinyl chloride into...

Continue reading...

By Shyla Cadogan The human gut is integral to just about every part of the body, but especially our immune system when you consider that roughly 70 percent of it lies within the gut. In a surprising discovery, Harvard Medical researchers are demonstrating how gut...

Continue reading...

Illuminating the pitfalls of the mind in felt and gingerbread.

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Real generosity toward the future lies in giving all to the present, Albert Camus wrote as he considered what it really means to be in solidarity with justice an elegantly phrased reminder that the decisions we make today are the only fulcrum by which we move the outcomes of tomorrow. And yet the greatest pitfall of human consciousness might be our habitual forgetting of this fundamental fact.

In 1950, two mathematicians working on game theory devised a cruelly brilliant thought experiment demonstrating just how poorly we manage to calibrate future outcomes for our own best interests, exposing a secret underground of consciousness where mathematics and morality converge. Known as The Prisoners Dilemma, it illuminates the complex dynamics that govern loyalty, betrayal, collaboration, and trust dynamics that play out in myriad subtle ways across our everyday lives.

The classic thought experiment comes alive with unexpected delight in this animated short film from TED-Ed by economist Lucas Husted and animators Ivana Bonjak and Thomas Johnson Volda:

Complement with philosopher Martha Nussbaum on the emotional machinery of trust and the only fruitful response to betrayal, then revisit other animated adaptations of classic thought experiments: The Ship of Theseus (exploring what makes you you), Platos Cave (exploring the central mystery of consciousness), Boltzmanns Brain Paradox (exploring whether reality is a hallucination), The Infinite Hotel Paradox (exploring the mind-bending nature of infinity), and Marys Room (exploring the limits of knowledge).

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donating = loving

For a decade and half, I have been spending hundreds of hours and...

I received a request from Apexel to review a phone accessory that connects to microscopes, telescopes, or binoculars. I replied to inform them that I had none of those pieces of equipment but I might be interested in reviewing a macro or microscope attachment to mobile phones.

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Click here to go see the bonus panel!

Hovertext:
The weird thing is he was originally just printing teeth for the pure delight before he discovered the opportunity for savings.

Today's News:

Welcome to Craft Schooling Sunday, thanks so much for joining me here! With the very festive Jewish holiday of Purim coming Monday night, the pressure is on to prepare, though with no young children around, costumes are on hold, until...

The bank is discontinuing its crypto payment network, claiming the termination is a risk-based decision.

This bucket bag pattern is the ideal project for those of you who would like to experiment with different materials.  A couple of weeks ago I showed you a round bag made with cord.  This time I am using upholstery fabric which is a very short pile velour to see Continue reading

Reboot of The Proud Family Cartoon Dedicates an Episode to Autism Awareness

The early 2000s animated series The Proud Family celebrated Blackness and represented Black families on screen. Airing on the Disney Channel, it also tackled serious subjects such as bullying, religion, and homelessness. Its new reboot The Proud Family: Louder and Prouder is no different. One episode, in particular, has recently gained traction online for its representation of the autism spectrum and its candid conversation on autism diagnoses.

In the episode, the family becomes concerned with young BeBes lack of fear. They are recommended to see child psychologist Dr. Lord, who says that BeBe is showing signs of being on the autism spectrum. A short clip from the episode was shared on Twitter, where parents Oscar and Trudy first hear and respond to the diagnosis. Oscar has trouble understanding the diagnosis and accuses Dr. Lord of calling BeBe stupid. Oscar initially wants to leave, calling the psychologist a quack.

Eventually, Oscar sits to listen to Dr. Lord, who explains that her tests show BeBe is incredibly intelligent, curious, and fearless. She states, all an autism diagnosis means is Bebe will need a little extra effort and attention. Dr. Lord also adds needing support doesnt mean lack of ability, and emphasizes the importance of the family believing in BeBe, as well as teaching and helping him.

The clip ends with Trudy and Oscar saying goodbye to BeBe as they...

The latest digital cameras boast ever-higher resolutions, better performance in low light, smart focusing and shake reduction and theyre built right into your smartphone.

[Read More]

Heartwarming Video Shows Jack Black and Terminally Ill Fan Singing School of Rock Song Together

 

Ver esta publicacin en Instagram

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2022 was not a bad year for the camera industry with sales hovering above those made in 2021. But for 2023 CIPA expects camera shipments to drop by 7,6%. System camera sales and lens sailed will drop by 3,5%. Its likely inflation and the upcoming slow down of the economy will be the major factor

The post CIPA predicts a slight decrease in camera sales for 2023 appeared first on mirrorlessrumors.

Thank you for reading. I can't say it enough.


Hark! A Vagrant, such as it is, is an archive website now. I didn't think it would be when I stepped away to work on other projects, but (not to kill the light mood around here) 2016-2018 were very difficult years in a personal sense, and emerging on the other side, I feel like this is a project that has run its course. I am so very grateful for all that this comic and my readers have given me, they have given me a career, joy, and more than I ever dreamed.

I'm still working on a graphic novel, and picture books for children. I miss making humour comics, but coming back to them, I will have to figure out what that will look like. These comics go back to my early 20s, and I am a different person. In a sense that's exciting. I'll figure it out, and I hope I'll see you there. Hark! is only one project, I personally am not going anywhere. And maybe next time I'll choose a title that I won't have to repeat ten times to people, a bright prospect.

I'd like to dedicate this archive to my sister Becky Beaton, who we lost in 2018, and who always believed in me. I love you, always.

-Kate

As it happens, boring Nelly and self absorbed Lockwood are really the last two people you would want as narrators. Sucks to be you, reader! I guess Heathcliff gives his perspective once, but mostly it's these two clowns and Isabella's letter from inside the madhouse.




As promised, here are the kid and baby items new to the store, for little Scholastic fans! Along with the plushes, I hope you find something for my littlest readers. Here is the link!

The part of the book leading to Cathy's death is the most interesting, isn't it? I have read chapters over and over.

Here's a collection of essays, an old one but a good one, if you want to start somewhere in thinking about it: 20th Century Interpretations of Wuthering Heights. In all libraries, everywhere. It has in it, though you can just google it up too, Charlotte's 1850 preface to the book in defence of it but courting the morals of the time and explaining why it is so ...different. "Wuthering Heights: Sorry, Sorry, Just Give It A Chance OK?" Then go read all the essays deconstructing that. Then go down the deconstructing rabbit hole until you have no idea what you think anymore anyway. Then watch Netflix or something because your brain broke. Well that's how I do it.


Some people have sent me pictures of pretty great Princess Pinecone and Pony costumes for Halloween. Pumpkins too! I'm so delighted to get those. I treasure 'em, thank you!




We have new plushes (see I made a new button with my computer skills), and new kids shirts coming in to Topatoco soon as well! I haven't really mentioned this before, but stores in the real world can also pick up my things to put on the shelves, through our wholesale department. And I'd love to see more of that, I get asked about it a lot! Well it's no problem, just go HERE and thanks as always for stopping by!

More Wuthering to come!

Here we are, back at Wuthering Heights after an extended leave. Heathcliff has come home and everyone is reasonable and I don't really see trouble brewing at all.

Thank you all who picked up King Baby!! I went on a book tour to schools and stores, and I loved all the little ones so much. I drew some comics about it: one
two
three
four

We have new plushes (see I made a new button with my computer skills), and new kids shirts coming in to Topatoco soon as well! I haven't really mentioned this before, but stores in the real world can also pick up my things to put on the shelves, through our wholesale department. And I'd love to see more of that, I get asked about it a lot! Well it's no problem, just go HERE and thanks as always for stopping by!

More Wuthering to come!

Ahoy there! Allow me to write a bit here! But first, the image above speaks the truth. KING BABY is coming soon from Scholastic books, and Walker books in the UK! It is my second picture book, and its a lot of fun. I hope you'll pick it up!

Well, if you've been around here long enough, you know that this website just updates at random and at this point, not often like many comics you probably read online. I've been doing Hark! A Vagrant for almost nine years, which is crazy to me. And the longer I've done it, the longer it takes to make a comic. I know they look off the cuff, people reviewing my books make a point of saying so! But it's a lot of work for this gal, a full time job when it's going at a rate that you'd probably like to see. Lots of days reading and writing and trying to come up with things, lots of ideas you've spent days on thrown in the garbage can. And when you're done, another blank page.

Hark! is always in the back of my head when I'm working on anything else, and I find myself wracked with guilt for not keeping the updates coming, I have one foot here and one foot there. This push and pull, I have to accept, makes anything I'm working on suffer. And I've been trying to figure out a solution to this! Something better than slow work all around. Because if I'm honest, I'm scared that if I leave this site alone too long, I'll lose something very precious to me.

You.

I've worked a long time to bring you here, and you've been good to come here and read my comics and support my work. I feel that we have built a relationship, my readers and I, it's very important to me, and I never want to put it in peril. So what to do?

Right now I'm working on a tv show pitch, kids book ideas, and my own graphic novel. I don't know what will come together in the end for the first two, and I've been down the tv road before, it's a lot of time for something that might not happen and that you can't really talk about (sorry!). But maybe it will work out! You have to try right?

But the main thing is the graphic novel, which is a memoir...

We'll get back to Mary Anning later. Is Kelis' milkshake song a gift to humanity, or what?

I had a lot of fun with this on twitter, so I just kept on going with it. But you know, I'm always kind of touched by how strongly fans support their favourite characters, and there is a lot of love for Cloak and Dagger, and you can see why because there are some pretty great things about that pair. But that costume, come on, it's a big old slice of tit window pie. They don't always dress Dagger like that, but yeah they mostly do! But they probably won't on the tv show!

I didn't dwell on Cloak very much in a comic about tit windows, but, here's something. I tweeted this essay a while ago when I read it, but Cloak's lack of a body really brought it to mind again, and you should totally read it, though mostly it is about the character Cyborg, it is relevant here too:

Humanity Not Included: DC's Cyborg and the Mechanization of the Black Body by Robert Jones, Jr.

I wouldn't say these two follow the rules of medieval society exactly, but they are my favourite pair of dirty peasants. And at least in reality they would have lived in a time without the cursed plague of KEEP CALM. A better time.

Today's book recommendation is Ian Mortimer's classic The Time Traveller's Guide to Medieval England. It's so good! And if you think you don't like reading history, this one will make you think again, it's so entertaining and engaging.

Here is a comic about a man I admire very much! Karl Heinrich Ulrichs was an early champion of LGBT rights, and maybe the first person to speak publicly for them as he did in Munich in 1867. The last picture there is the place where he spoke. He used the word "Urning" for gay men, a term he coined, because even the word "homosexual" wasn't invented yet (it would be soon after). I only found out about him last fall, which is surprising and also sadly not surprising. But he was really amazing, I'm sure you will agree.

Hark! A Vagrant is a strange mix, sometimes the comics are straight jokes and sometimes, like here, I just want to talk about someone I think is great in a way that's easy to pick up on - comics are great for that! And I tell you what, I got so much out of this particular collection, of all the things I read. Here is a link:

Karl Heinrich Ulrichs:
Urning Pride and the First Known Gay Activist
Translated and Edited by Michael Lombardi-Nash, PhD

The document is a mix of things, essays and Karl's own writings and I think you will like it very much. I'm going to leave you with the epitaph on the stone his friends put up for him, he had many friends and admirers. It reads like a little affectionate biography.


Karl Henrich Ulrichs
who was born in Westerfeld near East Friesland
He distinguished himself and became renowned among
his equals by his mental faculties in the humanities and other disciplines
through instruction he received in Gottingen and Berlin.
He was concerned about new problems in anthropology and jurisprudence.
He had a remarkable sense of duty.
He was not elevated to prosperity nor was he humbled
by the attacks from his adversaries.
As a pauper he left the region of Hanover and went into exile.
He traveled through a great part of Europe.
He displayed everywhere a model character by his knowledge and virtue.
Finally he came to live in Aquila in central Italy to live for a long time.
He edited a Latin journal titled "Alaudae...

Hello! It's been a while.

If you're a fan of Joan of Arc (and I mean, who isn't? Who has ever been like her before or since?) you should definitely look up the 1928 movie, The Passion of Joan of Arc. Maria Falconetti as Joan gives what is widely regarded as one of the best performances on film, ever - though certainly at a cost. Mesmerizing.

Hey, ponies are back in stock! They were out for a while, but they are back! woop woop woop!

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